Results 201 to 210 of about 135,650 (305)

ALDH2 inhibits FASN stabilization via the E3 ligase CBL to suppress lipid accumulation and liver cancer development. [PDF]

Biol Direct
Wang Y, Li L, Qu F, Hua T, Chen C, Yang L, Jiang R, Liu X, Cheng P, Min H, Wang Y, Pan X, Sun D, Tang R, Liu R, You H, Kong F.   +16 more
europepmc   +1 more source

E3 ubiquitin ligase; SMAD specific E3 ubiquitin protein ligase 2 (SMURF2); NEDD4 family E3 ubiquitin-protein ligase (RSP5) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

The many faces of the GID/CTLH E3 ligase complex. [PDF]

Biochem Soc Trans
Alpi AF, Chrustowicz J, Sherpa D, Schulman BA.   +3 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

E3 ligase LMO7 enhances temozolomide sensitivity by promoting MGMT degradation in lung cancer. [PDF]

J Biol Chem
Li J, Feng X, Deng Y, Chen B, Miao L, Liu Z, Sun Z, Hu L, Ma J, Zeng L, Wang X, Zhao Y.   +11 more
europepmc   +1 more source

E3 ubiquitin ligases and asthma relief

American Journal of Respiratory Cell and Molecular Biology
openaire   +3 more sources

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

E3 ligase Praja1 mediates ubiquitination and degradation of microtubule-associated protein tau. [PDF]

FEBS J
Aoki S, Onodera W, Takashima A, Kawasaki K, Imadegawa K, Kurahashi H, Oishi M, Asahi T, Soeda Y.   +8 more
europepmc   +1 more source