Results 211 to 220 of about 211,577 (291)

The RING-finger domain of Arabidopsis RMR functions as an E3 ligase essential for post-Golgi trafficking. [PDF]

J Biol Chem
Chen S, Zeng Y, Wong HY, Chen Y, Yang L, Luo F, Gao C, Jiang L, Wong KB.   +8 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase RNF130 [PDF]

, 2020
openaire   +1 more source

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

Developmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez, Niusha Banoukh, Fiona Mensching, Robert V. Skibbens, M. Kathryn Iovine   +4 more
wiley   +1 more source

Skeletal Muscle-Specific Deletion of E3 Ligase Asb2 Enhances Muscle Mass and Strength. [PDF]

J Cachexia Sarcopenia Muscle
Jang HR, Park SY, Lee Y, Lee D, Lee J, Cho Y, Choi CS, Lee HY.   +7 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase CCNB1IP1 [PDF]

, 2020
openaire   +1 more source

Isolated absence epilepsy associated with a de novo FBXW7 missense variant in the F‐box domain

Epilepsia Open, EarlyView.
Abstract The FBXW7 gene encodes a substrate‐recognition component of the Skp1‐Cul1‐F‐box (SCF) E3 ubiquitin ligase complex, which targets key regulatory proteins for proteasomal degradation. Recently, loss‐of‐function FBXW7 variants have been associated with a novel neurodevelopmental disorder characterized by heterogeneous clinical features.
Anees Muhammad, Mohammad Sadegh Shams Nosrati, Alireza Dostmohammadi, Francesca Madia, Maria Margherita Mancardi, Stefania Fornarino, Luca Bosisio, Zahra Hoseini Tavassol, Mir Davood Omrani, Federico Zara, Marcello Scala   +10 more
wiley   +1 more source

Correction to RING-Type E3 Ligase OsRFPH2-6 Ubiquitinates Nuclear Factor Y Subunit OsNF-YA1 to Suppress Rice Immunity. [PDF]

Mol Plant Pathol
europepmc   +1 more source

The E3 ligase HECTD4 regulates COX-2-dependent tumor progression and metastasis. [PDF]

Proc Natl Acad Sci U S A
Vuille JA, Tanriover C, Antmen E, Micalizzi DS, Ebright RY, Animesh S, Morris R, Hajizadeh S, Nicholson ZJ, Russell HC, Zaniewski EF, Wittner BS, Wesley BK, Kwak JE, Grünewald J, Szalay RN, Fox DB, Yang M, Joung JK, Gulhan DC, Elia AEH, Haas W, Oh E, Maheswaran S, Haber DA.   +24 more
europepmc   +1 more source

Diterpenoid Diversity across Land Plants

Helvetica Chimica Acta, EarlyView.
Here we bridge the knowledge of diterpene chemical diversity, biosynthesis, and evolution from nonvascular mosses and liverworts to that known from vascular plants. ABSTRACT The diverse array of diterpenoid natural products stems from the ease of manipulating the promiscuity of diterpene cyclases.
Anita Berg, Chad K. Papenfuhs, Amy E. Fraley   +2 more
wiley   +1 more source

Therapeutic potential of allosteric HECT E3 ligase inhibition. [PDF]

Cell
Rothman AMK, Florentin A, Zink F, Quigley C, Bonneau O, Hemmig R, Hachey A, Rejtar T, Thaker M, Jain R, Huang SM, Sutton D, Roger J, Zhang JH, Weiler S, Cotesta S, Ottl J, Srivastava S, Kordonsky A, Avishid R, Yariv E, Rathi R, Khvalevsky O, Troxler T, Binmahfooz SK, Kleifeld O, Morrell NW, Humbert M, Thomas MJ, Jarai G, Beckwith REJ, Cobb JS, Smith N, Ostermann N, Tallarico J, Shaw D, Guth-Gundel S, Prag G, Rowlands DJ.   +38 more
europepmc   +1 more source