Results 221 to 230 of about 171,834 (303)

The E3 ubiquitin ligase STUB1 inhibits Senecavirus A replication by mediating VP1 ubiquitination and proteasomal degradation. [PDF]

J Virol
Zeng P, Mao J, Guo J, Yang X, Shi Y, Wang X, Song J, Zhou J, Hou L, Liu J.   +9 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase AMFR [PDF]

, 2020
openaire   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

E3 ubiquitin ligase TRIM47 promotes intrahepatic cholangiocarcinoma progression by ubiquitinating fumarate hydratase and modulating macrophage polarization. [PDF]

J Biol Chem
Fu Y, Wu J, Shi J, Jia C.
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase RNF146 [PDF]

, 2020
openaire   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

Structural basis for E3 ubiquitin ligase UHRF1 binding to nucleosome core particle and histone H3 ubiquitination. [PDF]

J Biol Chem
Shikimachi R, Matsuzawa S, Onoda H, Konuma T, Yamagata A, Shirouzu M, Yamaguchi K, Arita K.   +7 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase UHRF1 [PDF]

, 2020
openaire   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

LRRC58 defines an E3 ubiquitin ligase complex sensitive to cysteine abundance

Ramage DE, Wieske LH, Crowe C, Christensen JB, von Wilmowski TA, Grant DW, Bannister Z, Nakasone MA, Haubrich K, Dorward M, Tchasovnikarova IA, Weekes MP, Bayin NS, Ciulli A, Timms RT.   +14 more
europepmc   +1 more source