Results 241 to 250 of about 223,299 (305)

AMOTL2 inhibits lymph node metastasis in gastric cancer by suppressing TGF-β/Smad signaling and is destabilized by the E3 ubiquitin ligase SMURF1. [PDF]

Int J Biol Sci
Wang H, Yang B, Lin C, Wang Y, Lu Y, Li J, Li J, Yu K, Wang M, Liu P, Wang Y, Li Y.   +11 more
europepmc   +1 more source

Serum Starvation Promotes the Proteolysis of OGT by Activating AMPK and the CUL1/SKP1/SKP2 E3 Ubiquitin Ligase in 3T3-L1 Cells. [PDF]

Biomol Ther (Seoul)
Ngo HH, Le DQ, Nam LB, Keum YS.
europepmc   +1 more source

OTULIN protects hyperoxia-induced neonatal lung injury and modulates mitochondrial protein OPA1 in association with the E3 ubiquitin ligase RNF31. [PDF]

Cell Mol Biol Lett
Huang L, Liu Q, Zhang A, Liu Y, Huang F, Wang J, Tan M, Wang D, Zhao M, Wu X.   +9 more
europepmc   +1 more source

E3 Ubiquitin Ligase Nedd4-2 Exacerbates Seizure-Induced Mitochondrial Defects in an Alzheimer's Disease Mouse Model. [PDF]

J Neurochem
Wang Y, Zhu J, Lizarazo S, Lee KY, Wong O, Azim S, Yook Y, Kumar V, Tsai NP.   +8 more
europepmc   +1 more source

Construction of a robust sepsis prognostic classifier based on E3 ubiquitin ligase-related genes. [PDF]

Front Mol Biosci
Xue H, Chen L, Zhao X, Zhu F.
europepmc   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

<i>Shigella flexneri</i>-Encoded E3 Ubiquitin Ligase IpaH2 Reveals Plakophilin-2 as a Host Restriction Factor for Sindbis Virus. [PDF]

Int J Mol Sci
Embry A, Rex EA, Schad DF, Deng DM, Alto NM, Gammon DB.   +5 more
europepmc   +1 more source

Comparative Analysis of Salmonella typhimurium‐Induced Transcriptomic Changes in the Spleen of Beijing‐You Chickens and Guang Ming Broilers

Animal Research and One Health, EarlyView.
This study analyzed the spleen transcriptomes of different chicken breeds, identified key differentially expressed genes (EGR1, FOS, and DUSP1) that regulate resistance to Salmonella infection, and elucidated the underlying regulatory mechanisms, thereby providing new targets for disease‐resistant breeding in poultry.
Zixuan Wang, Man Deng, He Geng, Jumei Zheng, Xiang Li, Yaping Wang, Qinghe Li, Guiping Zhao, Qiao Wang   +8 more
wiley   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

E3 ubiquitin ligase NEDD4 inhibits PEDV infection through ubiquitination and degradation of the viral primase NSP8. [PDF]

J Virol
Guo X, Zhao X, He J, Lu Y, Jin S, Ma Z, Li Z, Zheng Z, Li Y, Feng Y, Xu L, Liu X, Zhang J, Wei Z, Zheng H, Xiao S.   +15 more
europepmc   +1 more source