Results 271 to 280 of about 176,319 (351)

E3 Ubiquitin-Protein Ligase RNF146 [PDF]

, 2020
openaire   +1 more source

High-throughput screening of E3 ubiquitin ligases identifies TRIM48 as a novel negative regulator of RIG-I signaling

Guandi Wu, Jamie Frankish, Joschka Willemsen, Dominik Ricken, Jonas P. Becker, Darius Schweinoch, Jürgen Beneke, Sandra Wüst, Nina Beil, Petr Matula, Karl Rohr, Holger Erfle, Lars Kaderali, Marco Binder   +13 more
openalex   +1 more source

Challenges and opportunities for the diverse substrates of SPOP E3 ubiquitin ligase in cancer. [PDF]

Theranostics
Yang X, Zhu J, Tao X, Gao F, Cai Y, Lv Y, Xie S, Xie K, Lan T, Han J, Wu H.   +10 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase UHRF1 [PDF]

, 2020
openaire   +1 more source

Hypomethylating agents in vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS): A systematic review

British Journal of Haematology, EarlyView.
Summary VEXAS syndrome (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) is an X‐linked, systemic, haemato‐inflammatory syndrome caused by somatic mutations in the UBA1 gene. No standardized treatment guidelines exist, but evidence is emerging that treatment with hypomethylating agents (HMAs) can induce improvement of the inflammatory symptoms,
Fieke W. Hoff, Roochi Trikha, Emma M. Groarke, Bhavisha A. Patel   +3 more
wiley   +1 more source

The E3 ubiquitin ligase MARCH2 controls TNF-α mediated inflammation by autoubiquitination. [PDF]

Cell Commun Signal
Chathuranga K, Rathnapala P, Weerawardhana A, Kim TH, Seong Y, Gayan Chathuranga WA, Subasinghe A, Haluwana DK, Gamage N, Choi YJ, Jung JU, Lee JS.   +11 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase TRIM36 [PDF]

, 2020
openaire   +1 more source

The Magnaporthe oryzae Effector AvrPiz-t Targets the RING E3 Ubiquitin Ligase APIP6 to Suppress Pathogen-Associated Molecular Pattern–Triggered Immunity in Rice

, 2012
Chan Ho Park, Songbiao Chen, Gautam Shirsekar, Bo Zhou, Chang Hyun Khang, Pattavipha Songkumarn, Ahmed J. Afzal, Yuese Ning, Ruyi Wang, Maria Bellizzi, Barbara Valent, Guo‐Liang Wang   +11 more
openalex   +2 more sources

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

E3 ubiquitin ligase Listerin regulates macrophage cholesterol efflux and atherosclerosis by targeting ABCA1. [PDF]

J Clin Invest
Cao L, Zhang J, Yu L, Yang W, Qi W, Ren R, Liu Y, Hou Y, Cao Y, Li Q, Wang X, Zhang Z, Li B, Sui W, Zhang Y, Gao C, Zhang C, Zhang M.   +17 more
europepmc   +1 more source