Results 181 to 190 of about 67,820 (304)

Role of the Mitochondrial E3 Ubiquitin Ligases as Possible Therapeutic Targets in Cancer Therapy. [PDF]

Int J Mol Sci, 2023
Di Gregorio J, Appignani M, Flati V.
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase DTX1 [PDF]

, 2020
openaire   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

CUL3^LRB E3 ubiquitin ligases control thermosensory growth in <i>Arabidopsis</i> by differentially regulating HY5 and PIF4 protein stability. [PDF]

Sci Adv
Singhal C, Upadhyaya G, Rajkumar MS, Modak A, Sethi V, Singh S, Das D, Jain M, Gangappa SN.   +8 more
europepmc   +1 more source

E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation. [PDF]

Viruses, 2023
Oswald J, Constantine M, Adegbuyi A, Omorogbe E, Dellomo AJ, Ehrlich ES.   +5 more
europepmc   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Emerging roles for E3 ubiquitin ligases in neural development and disease. [PDF]

Front Cell Dev Biol
Hale M, Bashaw GJ.
europepmc   +1 more source

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

Developmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez, Niusha Banoukh, Fiona Mensching, Robert V. Skibbens, M. Kathryn Iovine   +4 more
wiley   +1 more source

Tuning ubiquitin transfer by RING E3 ubiquitin ligases through the linchpin residue. [PDF]

Life Sci Alliance
Nakasone MA, Buetow L, Gabrielsen M, Ahmed SF, Majorek KA, Sibbet GJ, Smith BO, Huang DT.   +7 more
europepmc   +1 more source

The role of E3 ubiquitin ligases in bone homeostasis and related diseases. [PDF]

Acta Pharm Sin B, 2023
Dong Y, Chen Y, Ma G, Cao H.
europepmc   +1 more source