Results 91 to 100 of about 247,106 (313)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Guyan Eagle Stores

open access: yes, 1950
This scrip is from the Guyan Eagle Stores with a value of 1¢.https://scholarworks.moreheadstate.edu/kilgore_scrip_collection/1064/thumbnail ...
Guyan Eagle Stores
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Audiovisual - Digital Materials - Faculty/Student Introductions - Eagle, Herb, 2007

open access: yes, 2014
Introductions by Herbert Eagle discussing his work/contribution to and experiences with Residential College and opportunities it offers to students. Created for the college's website shortly before the 40th anniversary celebration.http://deepblue.lib ...
University of Michigan. Residential College
core  

Biología reproductiva del águila Geranoaetus melanoleucus (Aves: Accipitridae) en Chile central Breeding biology of the black-chested eagle Geranoaetus melanoleucus (Aves: Accipitridae) in central Chile

open access: yesRevista Chilena de Historia Natural, 2001
Durante dos años (julio 1987­enero 1989) se estudió la biología reproductiva del águila (Geranoaetus melanoleucus) en San Carlos de Apoquindo, en Chile central. El inicio del período reproductivo se evidenció por un aumento del número de vuelos en pareja.
EDUARDO F. PAVEZ
doaj  

Apparent Survival of Territorial Golden Eagles Using Non‐Invasive Genetic Profiling

open access: yesEcology and Evolution
Conservation efforts for large raptors require robust estimates of fecundity, age at maturity and survivorship and population trajectories are often particularly sensitive to change in adult survival rates.
D. Philip Whitfield   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

[News Clip: Eagle Mountain]

open access: yes, 1960
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about the activation of the Eagle Mountain army air field in formal ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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