Results 1 to 10 of about 434,910 (305)
Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids [PDF]
Stem Cell Reports, 2019 Summary: Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear.
Pei-Ciao Tang +8 more
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The Role of FoxG1 in the Inner Ear [PDF]
Frontiers in Cell and Developmental Biology, 2020 Sensorineural deafness is mainly caused by damage to the tissues of the inner ear, and hearing impairment has become an increasingly serious global health problem.
Yanyan Ding +7 more
doaj +4 more sources
Scientific Reports, 2021 Hearing loss is a common disability affecting the world’s population today. While several studies have shown that inner ear gene therapy can be successfully applied to mouse models of hereditary hearing loss to improve hearing, most of these studies rely
Jianliang Zhu +6 more
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Fzd3 Expression Within Inner Ear Afferent Neurons Is Necessary for Central Pathfinding
Frontiers in Neuroscience, 2022 During development the afferent neurons of the inner ear make precise wiring decisions in the hindbrain reflective of their topographic distribution in the periphery.
Zachary A. Stoner +6 more
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Listy klinicke logopedie, 2020 Inner ear malformation comprises a broad group of disorders, the main symptom of which is hearing loss. The disorder occurs during the embryonic development of the auditory system. Only about 20 % of malformations can be diagnosed radiologically. Hearing
Dagmar Hošnová, Milan Urík
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Nanocarriers for Inner Ear Disease Therapy
Frontiers in Cellular Neuroscience, 2021 Hearing loss is a common disease due to sensory loss caused by the diseases in the inner ear. The development of delivery systems for inner ear disease therapy is important to achieve high efficiency and reduce side effects.
Xiaoxiang Xu +10 more
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Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear [PDF]
, 2005 An early and crucial event in vertebrate inner ear development is the acquisition of axial identities that in turn dictate the positions of all subsequent inner ear components.
Bok, Jinwoong +2 more
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Mouse Embryonic Fibroblasts-Derived Extracellular Matrix Facilitates Expansion of Inner Ear-Derived Cells [PDF]
Cell Journal, 2023 Objective: Previous reports showed that mouse embryonic fibroblasts (MEFs) could support pluripotent stem cell selfrenewaland maintain their pluripotency.
Junming Zhang +4 more
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Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
, 2018 Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
core +1 more source
Diagnostics, 2020 The diagnostics of inner ear diseases are primarily functional, but there is a growing interest in inner ear biomarkers. The present scoping review aimed to elucidate gaps in the literature regarding the definition, classification system, and an overview
Nahla A. Gomaa +4 more
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