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Editorial: Neuroimmunology of the Inner Ear [PDF]
© 2021 Perin, Marino, Varela-Nieto and Szczepek. Although the term was first officially used in 1982 (1), neuroimmunology is now a mature field that has gained immense traction in the past decade. Thanks to novel technological advances, the cellular and molecular mechanisms that mediate the crosstalk between the immune and nervous systems are ...
Paola Perin+6 more
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The inner ear and the neurologist [PDF]
Inner ear disorders are common and patients with vestibular failure often present to a neurology clinic because of their dizziness, gait unsteadiness and oscillopsia. Vestibular disorders can be divided into peripheral and central vestibular disorders.
Michael Gleeson+2 more
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Development of the inner ear [PDF]
The vertebrate inner ear is a sensory organ of exquisite design and sensitivity. It responds to sound, gravity and movement, serving both auditory (hearing) and vestibular (balance) functions. Almost all cell types of the inner ear, including sensory hair cells, sensory neurons, secretory cells and supporting cells, derive from the otic placode, one of
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Proteomics and the Inner Ear [PDF]
The inner ear, one of the most complex organs, contains within its bony shell three sensory systems, the evolutionary oldest gravity receptor system, the three semicircular canals for the detection of angular acceleration, and the auditory system ‐ unrivaled in sensitivity and frequency discrimination.
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Effects of Glucocorticoids on the Inner Ear [PDF]
Hypothesis: Recently, several lines of evidence have suggested that the inner ear is under hormonal control. It is likely that steroids have some influence on the inner ear.Background: Many clinicians have been empirically using steroids for the treatment of diseases associated with endolymphatic hydrops. The theoretical grounds for this are not clear,
Setsuko Takeda+2 more
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Autophagy in the Vertebrate Inner Ear [PDF]
Autophagy is a conserved catabolic process that results in the lysosomal degradation of cell components. During development, autophagy is associated with tissue and organ remodeling, and under physiological conditions it is tightly regulated as it plays a housekeeping role in removing misfolded proteins and damaged organelles.
Marta Magariños+9 more
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The Role of FoxG1 in the Inner Ear [PDF]
Sensorineural deafness is mainly caused by damage to the tissues of the inner ear, and hearing impairment has become an increasingly serious global health problem. When the inner ear is abnormally developed or is damaged by inflammation, ototoxic drugs, or blood supply disorders, auditory signal transmission is inhibited resulting in hearing loss ...
Yanyan Ding+7 more
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The Mechanics of the Inner Ear [PDF]
I AM much indebted to Prof. McKendrick for his exceedingly fair review of my monograph on the mechanics of the inner ear (NATURE, June 4, p. 114). One point, however, seems to require a reply on my part. Prof. McKendrick suggests that I should make “a huge model” of the cochlea.
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Herpes zoster oticus, herpes zoster cephalicus, Ramsay Hunt syndrome.
Arnold, Andreas+10 more
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Purinergic signaling in the inner ear [PDF]
Epithelial cells of the inner ear coordinate their ion transport activity through a number of mechanisms. One important mechanism is the autocrine and paracrine signaling among neighboring cells in the ear via nucleotides, such as adenosine, ATP and UTP.
Daniel C. Marcus, Jun Ho Lee
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