Results 111 to 120 of about 68,591 (217)

Biallelic Mutations in the Otogelin-Like Gene (OTOGL) Associated With Congenital Non-Syndromic Sensorineural Hearing Loss in a Chinese Family. [PDF]

Mol Genet Genomic Med
Dai X, Li J, Hu X, Cai W.
europepmc   +1 more source

Characteristics of Hearing Loss in Type 2 Diabetes Mellitus: A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Methods A systematic review of CINAHL, Cochrane Library, PubMed, and SCOPUS databases was conducted according to PRISMA guidelines to identify studies evaluating T2DM and hearing loss. Primary outcome measures included continuous measures (mean), proportions (%), proportional difference (∆), and relative risks (RR) with 95% confidence ...
Cory Hyun‐su Kim, Katherine L. Lauritsen, Shaun A. Nguyen, Ted A. Meyer, Evan C. Cumpston, Justin Pelic, Robert Labadie   +6 more
wiley   +1 more source

Transtympanic Injection of Antioxidant‐Eluting Microparticles for Otoprotection From Cisplatin Toxicity in a Mouse Model

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Cisplatin is a chemotherapeutic agent with the undesirable side effect of ototoxicity. Transtympanic injections of antioxidant formulations may provide local otoprotection. We tested a novel antioxidant‐eluting microparticle for its otoprotective capability from systemic cisplatin as measured by cochlear electrophysiology.
Eric Michael Smith, Carmen Boixo, Larry Hoffman, Ashley E. Kita   +3 more
wiley   +1 more source

Severe Hearing Loss in Children With Central Nervous System Tumors: A Population‐Based Cancer in Young People in Canada (CYP‐C) Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Children with central nervous system (CNS) tumors are prone to treatment‐related hearing loss (HL) and subsequent functional impairment. This study reports a dedicated population‐based analysis of CNS tumor‐specific rates and predictors of early severe HL.
Hallie Coltin, Ofélie Trudeau‐Ferrin, Sébastien Perreault, Lucie Lafay‐Cousin, Derek S. Tsang, Samuele Renzi, Valérie Larouche, Craig Erker, Juliette Hukin, Randy Barber, Paul C. Nathan, Annie Huang, Eric Bouffet, Vijay Ramaswamy   +13 more
wiley   +1 more source

Hereditary kidney disease with auditory abnormalities: analysis of mutations and clinical phenotypes. [PDF]

BMC Med Genomics
Bi J, Guo W, Ji P, Xie Y.
europepmc   +1 more source

Ammonia to Hydrogen Conversion in a Ferroelectric Packed‐Bed Plasma Reactor: The Effect of a High‐Permittivity Effective Medium Material

Plasma Processes and Polymers, EarlyView.
Ambient ammonia‐to‐hydrogen conversion is achieved in a packed‐bed ferroelectric plasma reactor. A Ru/Al2O3 coating on PZT pellets acts as a high‐permittivity effective medium, enhancing plasma current and boosting yield to 40%. Catalytic effects are negligible, and conversion is driven by permittivity‐enhanced plasma electrical properties.
Paula Navascués, Mateo Ruiz‐Martín, Guillermo Regodón, Alberto Palmero, J. Cotrino, Agustín Rodríguez González‐Elipe, Ana Gómez‐Ramírez   +6 more
wiley   +1 more source

The Development of Inner Ear Membrane Analog for Experimental Otorhinolaryngology. [PDF]

Sovrem Tekhnologii Med
Riabinin AA, Rogovaya OS, Kryukov AI, Kunelskaya NL, Yanyushkina ES, Mischenko VV, Ilyin MM, Shershunova EA, Voyevodin VV, Nebogatkin SV, Pomanov KI, Vorotelyak EA.   +11 more
europepmc   +1 more source

Update on Gene Therapy in the Treatment of Hereditary Hearing Loss

Sensory Neuroscience, EarlyView.
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He, Shanying Han, Xinghong Liu, Xiaotong Huang, Wen Yang, Xinghua Tang, Chuan Dong, Jiangang Fan   +7 more
wiley   +1 more source

Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation

Sensory Neuroscience, EarlyView.
ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera, Nicole Ramones, Isabella Moceri, Sanjoy K. Bhattacharya   +3 more
wiley   +1 more source