Results 111 to 120 of about 441,758 (309)

Competence, specification and commitment in otic placode induction [PDF]

open access: yes, 2000
The inner ear is induced from cranial ectoderm adjacent to the hindbrain. Despite almost a century of study, the molecular mechanisms of inner ear induction remain obscure. We have identified four genes expressed very early in the anlage of the inner ear,
Bronner-Fraser, Marianne   +1 more
core  

Vestibular schwannoma and ipsilateral endolymphatic hydrops: an unusual association [PDF]

open access: yes, 2017
Vestibular schwannoma and endolymphatic hydrops are two conditions that may present with similar audio-vestibular symptoms. The association of the two in the same patient represents an unusual nding that may lead clinicians to errors and delays in ...
ALTISSIMI, Giancarlo   +8 more
core   +2 more sources

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen   +12 more
wiley   +1 more source

A unique radioprotective effect of resolvin E1 reduces irradiation-induced damage to the inner ear by inhibiting the inflammatory response

open access: yesRadiation Oncology, 2020
Background In addition to the direct effects of irradiation, the induced inflammatory response may play an important role in the damage to the inner ear caused by radiotherapy for the treatment of head and neck cancers.
Jie Zhang   +8 more
doaj   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

open access: yesAdvanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li   +12 more
wiley   +1 more source

Flexibility within the middle ears of vertebrates [PDF]

open access: yes, 2013
Introduction and aims: Tympanic middle ears have evolved multiple times independently among vertebrates, and share common features. We review flexibility within tympanic middle ears and consider its physiological and clinical implications.
Baird   +36 more
core   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

open access: yesAdvanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu   +8 more
wiley   +1 more source

Towards a complete 3D morphable model of the human head [PDF]

open access: yesarXiv, 2019
Three-dimensional Morphable Models (3DMMs) are powerful statistical tools for representing the 3D shapes and textures of an object class. Here we present the most complete 3DMM of the human head to date that includes face, cranium, ears, eyes, teeth and tongue.
arxiv  

3D Printed Ear Canal Model [PDF]

open access: yes, 2017
A multi-material ear canal model was designed and created from CT scans of an actual patient. This ear canal model serves as a training model for trainees, surgeons and doctors to develop a better understanding of the anatomy and physiology of the ear ...
Ali, Ahmad   +2 more
core   +1 more source

Evaluation of How Anesthesia Affect Body Temperature in Sows Using Infrared Thermography [PDF]

open access: yes, 2018
The objective of this experiment was to determine the relationship between rectal temperature and infrared temperature measured on the inner eye, center- and ear base of sows undergoing anesthesia. A total of six sows were used.
Bruns, Caitlyn   +8 more
core   +3 more sources

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