Results 91 to 100 of about 1,367,224 (352)

Inner-Ear Disorders Presenting with Air–Bone Gaps: A Review [PDF]

, 2020
Air–bone gaps (ABGs) are commonly found in patients with conductive or mixed hearing loss generally due to outer- and/or middle-ear diseases such as otitis externa, tympanic membrane perforation, interruption or fixation of the ossicular chain, and ...
Cavaliere, Matteo, CASSANDRO, Ettore, Matteo Cavaliere, Arianna Di Stadio, cassandro, claudia, Stadio, Arianna Di, Marco de Vincentiis, Di Stadio, Arianna, Gioacchini, Federico Maria, Ettore Cassandro, Troisi, Donato, Antonio Greco, Massimo Ralli, Scarpa, Alfonso, greco, antonio, Federico Maria Gioacchini, Claudia Cassandro, Ralli, Massimo, Alfonso Scarpa, de Vincentiis, marco, Donato Troisi   +20 more
core   +1 more source

Probing the Xenopus laevis inner ear transcriptome for biological function

BMC Genomics, 2012
Background The senses of hearing and balance depend upon mechanoreception, a process that originates in the inner ear and shares features across species.
Powers TuShun R, Virk Selene M, Trujillo-Provencio Casilda, Serrano Elba E   +3 more
doaj   +1 more source

Generation of inner ear organoids with functional hair cells from human pluripotent stem cells

Nature Biotechnology, 2017
The derivation of human inner ear tissue from pluripotent stem cells would enable in vitro screening of drug candidates for the treatment of hearing and balance dysfunction and may provide a source of cells for cell-based therapies of the inner ear. Here
Karl R. Koehler, J. Nie, Emma Longworth-Mills, Xiao-ping Liu, Jiyoon Lee, J. Holt, E. Hashino   +6 more
semanticscholar   +1 more source

Waveguide Photoactuators: Materials, Fabrication, and Applications

Advanced Robotics Research, EarlyView.
Waveguide photoactuators convert guided light into mechanical motion. Their tethered‐flexible design enables minimally invasive surgery and confined‐space robotics. This review aims to guide materials selection, device design, and system integration, accelerating the transition of waveguide photoactuators from laboratory prototypes to versatile ...
Minjie Xi, Hemin Pan, Yang Zong, Yongfeng Mei, Jizhai Cui   +4 more
wiley   +1 more source

Exocytosis at mammalian vestibular ribbon synapses shows a high-order Ca2+ dependence and does not require synaptotagmin-4 [PDF]

, 2018
Inner ear sensory synapses faithfully transduce information over a wide range of stimulus intensities for prolonged periods of time. The efficiency of such demanding and stringent exocytotic activity depends on the presence of specialised presynaptic ...
Sergio Masetto, Walter Marcotti, Stuart L. Johnson, Paolo Spaiardi   +3 more
core  

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, EarlyView.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

Autoimmune inner ear disease (AIED): A diagnostic challenge

International Journal of Immunopathology and Pharmacology, 2018
Autoimmune inner ear disease (AIED) has been defined as a condition of bilateral sensorineural hearing loss (SNHL), caused by an ‘uncontrolled’ immune system response.
A. Ciorba, Virginia Corazzi, C. Bianchini, C. Aimoni, S. Pelucchi, P. Skarżyński, S. Hatzopoulos   +6 more
semanticscholar   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Genomic analysis of the function of the transcription factor gata3 during development of the Mammalian inner ear [PDF]

, 2009
We have studied the function of the zinc finger transcription factor gata3 in auditory system development by analysing temporal profiles of gene expression during differentiation of conditionally immortal cell lines derived to model specific auditory ...
Kneebone, A., Hikke Van Doorninck, Grace Lawoko-Kerali, Lawoko-Kerali, G. (Grace), Rivolta, Marcelo, Van Doorninck, H., Milo, M. (Marta), Milo Marta, Van Doorninck Hikke, Johnson, Claire, Doorninck, J.H. (Hikke) van, Johnson, C. (Claire), Milo, M., Lawoko-Kerali, Grace, Niranjan Mahesan, Holley Matthew, Cacciabue-Rivolta, Daniela, Van Doorninck, Hikke, Adam Kneebone, Mahesan Niranjan, Lawoko-Kerali, G., Holley, M., Milo, Marta, Lawoko-Kerali Grace, Johnson Claire, Marta Milo, Kneebone Adam, Kneebone, Adam, Niranjan, M., Holley, Matthew, Holley, M. (Matthew), Claire Johnson, Cacciabue-Rivolta, D. (Daniela), Daniela Cacciabue-Rivolta, Niranjan, M. (Mahesan), Rivolta Marcelo, Rivolta, M., Niranjan, Mahesan, Marcelo Rivolta, Cacciabue-Rivolta Daniela, Cacciabue-Rivolta, D., Rivolta, M. (Marcelo), Matthew Holley, Kneebone, A. (Adam), Johnson, C.   +44 more
core   +1 more source

Inner ear pathologies impair sodium-regulated ion transport in Meniere’s disease

Acta Neuropathologica, 2018
Meniere’s disease (MD), a syndromal inner ear disease, is commonly associated with a pathological accumulation of endolymphatic fluid in the inner ear, termed “idiopathic” endolymphatic hydrops (iEH).
Andreas H. Eckhard, Mengyu Zhu, J. O'malley, G. Williams, J. Loffing, S. Rauch, J. Nadol, M. Liberman, Joe C. Adams   +8 more
semanticscholar   +1 more source