Results 121 to 130 of about 96,350 (311)

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science
The number of people with hearing loss disorders is enormous, causing great physical and mental stress to patients, as well as a huge social burden. Among these patients, hearing loss caused by inner ear lesions accounts for a large proportion. Therefore,
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
doaj   +1 more source

Inner Ear

, 2010
Herpes zoster oticus, herpes zoster cephalicus, Ramsay Hunt syndrome.
Arnold, Andreas, Arnold, Wolfgang, Bovo, Roberto, Ganzer, Uwe, Hamann, Karl-Friedrich, Iurato, Salvatore, Kiefer, Jan, Lamm, Kerstin, Livi, Walter, Martini, Alessandro, O'Donoghue, Gerard M.   +10 more
openaire   +3 more sources

Non conventional signal transmission at the mouse vestibular Type I hair cell - calyx synapse

, 2018
Vestibular sensory epithelia of Amniotes contain two types of hair cells, Type I and Type II, which differ in electrophysiological properties and synaptic contacts. Type I hair cells alone express a low-voltage activated outward rectifying K+ conductance,
Sergio Masetto, Elisa Tavazzani, Marco Manca, Giancarlo Russo, Paolo Spaiardi, Ivo Prigioni   +5 more
core  

Anatomical Study and Classification of Foramina of the Squamous Part of the Temporal Bone

Clinical Anatomy, EarlyView.
ABSTRACT The postglenoid foramen (PGF) is a rarely reported anatomical variant of the temporal bone, with limited data on its morphology, prevalence, and clinical relevance, particularly in non‐European populations. This study aimed to investigate the anatomy and frequency of foramina located on the squamous part of the temporal bone, including the PGF,
Tawanrat Paensukyen, Pattita Kanjanapaisan, Napawan Taradolpisut, Nutmethee Kruepunga, Benrita Jitaree, Pakpoom Thintharua, Arada Chaiyamoon, Athikhun Suwannakhan   +7 more
wiley   +1 more source

Eps8 regulates cochlear and vestibular hair cell development

, 2016
Deletion of Epidermal growth factor receptor pathway substrate 8 (Eps8), a gene involved in actin remodeling, causes deafness in mice. Cochlear inner hair cells from Eps8-knockout (KO) mice have abnormally short stereocilia and fail to acquire their ...
ZAMPINI, VALERIA, MANCA, MARCO, MASETTO, SERGIO, CONTINI, DONATELLA, RUSSO, GIANCARLO, Tavazzani, Elsa, Marcotti, Walter, SPAIARDI, PAOLO, PRIGIONI, IVO   +8 more
core  

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei

Developmental Dynamics, EarlyView.
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Jeong Han Lee, Ebenezer N. Yamoah, Jennifer Kersigo, Karen Elliott, Niya LaRoda, Gabriela Pavlinkova, Bernd Fritzsch   +6 more
wiley   +1 more source

Creatine supports propagation and promotes neuronal differentiation of inner ear progenitor cells

, 2014
Long-term propagation of inner ear-derived progenitor/stem cells beyond the third generation and differentiation into inner ear cell types has been shown to be feasible, but challenging.
Mina, Amir, Widmer, Hans Rudolf, Senn, Pascal, Di Santo, Stefano, Ducray, Angélique, Widmer, Hans R   +5 more
core   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source