Results 121 to 130 of about 1,367,224 (352)
The Blood-Labyrinth Barrier: Non-Invasive Delivery Strategies for Inner Ear Drug Delivery
PharmaceuticsThe inner ear is a relatively isolated organ, protected by the blood-labyrinth barrier (BLB). This barrier creates a unique lymphatic fluid environment within the inner ear, maintaining a stable physiological state essential for the mechano-electrical ...
Zhangyi Yi +3 more
doaj +1 more source
Radiation Oncology, 2020 Background In addition to the direct effects of irradiation, the induced inflammatory response may play an important role in the damage to the inner ear caused by radiotherapy for the treatment of head and neck cancers.
Jie Zhang +8 more
doaj +1 more source
Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction
Advanced Science, EarlyView.In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng +12 more
wiley +1 more source
Effect of cochlear implant electrode insertion on middle-ear function as measured by intra-operative laser Doppler vibrometry [PDF]
, 2009 Hypothesis: The aim of this study was to investigate the impact of cochlear implant electrode insertion on middle-ear low frequency function in humans.Background: Preservation of residual low frequency hearing with addition of electrical speech ...
Donnelly, N +6 more
core
Extraintestinal Crohn's Disease Mimicking Autoimmune Inner Ear Disease: A Histopathological Approach [PDF]
, 2010 Patients with autoimmune inner ear disease develop rapidly progressive sensorineural hearing loss over a period of several weeks or months, often accompanied by vestibular loss.
Dettmer, M +6 more
core +1 more source
Hearing Research, 2017 The cochlea and the vestibular organs are populated by resident macrophages, but their role in inner ear maintenance and pathology is not entirely clear.
K. Hirose, M. Rutherford, M. Warchol
semanticscholar +1 more source
From Flexible to Conformable Pressure Sensors: Mechanisms, Materials, and Biomedical Applications
Advanced Electronic Materials, EarlyView.This review highlights recent progress, challenges and future opportunities in pressure sensing for advanced biomedical applications. We summarize key transduction mechanisms and emerging material strategies, discuss representative wearable and implantable applications for continuous physiological monitoring and provide a focused perspective on barrier
Rishabh B. Mishra +2 more
wiley +1 more source
Integrated Environmental Assessment and Management, EarlyView., 2023 Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves +6 more
wiley +1 more source
Non conventional signal transmission at the mouse vestibular Type I hair cell - calyx synapse [PDF]
, 2018 Vestibular sensory epithelia of Amniotes contain two types of hair cells, Type I and Type II, which differ in electrophysiological properties and synaptic contacts. Type I hair cells alone express a low-voltage activated outward rectifying K+ conductance,
Sergio Masetto +5 more
core
Outlook and future of inner ear therapy
Hearing Research, 2018 Drug delivery to the inner ear is an ideal method to treat a wide variety of otologic conditions. A broad range of potential applications is just beginning to be explored.
Jenna Devare +2 more
semanticscholar +1 more source