Results 131 to 140 of about 434,910 (305)

Self‐Supervised Learning‐Based Framework for Speckle Reduction of Optical Coherence Tomography Images Using Frame Interpolation

Advanced Intelligent Systems, EarlyView.
In summary, a self‐supervised end‐to‐end framework for OCT image despeckling is proposed, without access to unpaired noisy–clean images or paired noisy–noisy images for training. The despeckling performance has been evaluated on 150 subjects from five retina datasets (121 subjects) and one middle ear dataset (29 subjects). Optical coherence tomography (
Zhiyi Jiang, Yifeng Hao, Jing Dai, Ka‐Wai Kwok   +3 more
wiley   +1 more source

Boron deficiency responses in maize (Zea mays L.) roots

Journal of Plant Nutrition and Soil Science, EarlyView., 2023
Abstract Background Boron (B) is an essential micronutrient for plants. Dicot plants respond to insufficient B supply by altering root architecture and root hair growth. How root systems of rather low‐B demanding monocot species such as maize (Zea mays L.) respond to B deficiency in terra has not been experimentally resolved, yet.
Manuela Désirée Bienert, Astrid Junker, Michael Melzer, Thomas Altmann, Nicolaus von Wirén, Gerd Patrick Bienert   +5 more
wiley   +1 more source

Auditory neuroscience: Development, transduction and integration [PDF]

, 2000
Hearing underlies our ability to locate sound sources in the environment, our appreciation of music, and our ability to communicate. Participants in the National Academy of Sciences colloquium on Auditory Neuroscience: Development, Transduction, and ...
Hudspeth, A. J., Konishi, Masakazu
core  

Speech Recognition with Cochlea‐Inspired In‐Sensor Computing

Advanced Intelligent Systems, EarlyView.
Traditional speech recognition methods rely on software‐based feature extraction that introduces latency and high energy costs, making them unsuitable for low‐power devices. A proof‐of‐concept demonstration is provided of a bioinspired tonotopic sensor for speech recognition that mimics the human cochlea, using a spiral‐shaped elastic metamaterial. The
Paolo H. Beoletto, Gianluca Milano, Carlo Ricciardi, Federico Bosia, Antonio S. Gliozzi   +4 more
wiley   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science
The number of people with hearing loss disorders is enormous, causing great physical and mental stress to patients, as well as a huge social burden. Among these patients, hearing loss caused by inner ear lesions accounts for a large proportion. Therefore,
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
doaj   +1 more source

Identification and Characterization of a Novel Biallelic SLC12A2 Variant Associated With Kilquist Syndrome (OMIM #619080)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone, Alessia Nisco, Luciana de Gennaro, Maria Tolomeo, Elisa Lorefice, Giuseppe Petrosillo, Silvia Russo, Donatella De Giovanni, Claudia Rita Catacchio, Francesca Romana Lepri, Mario Ventura, Simonetta Simonetti, Albina Tummolo, Maria Barile   +13 more
wiley   +1 more source

A Novel Missense Variant in LMX1A Leads to Autosomal Dominant Nonsyndromic Hearing Loss

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hereditary nonsyndromic hearing loss (NSHL) is a prevalent entity associated with over 150 known causative genes, including LMX1A, which has fewer than 10 reported pathogenic variants. Here we present a novel missense variant in LMX1A in a family of European descent with hereditary hearing loss. Clinical and family histories were obtained, and
Ryan Chen, Dayna Morel Swols, Guney Bademci, Mustafa Tekin   +3 more
wiley   +1 more source

Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Poor vascular health has been associated with age‐related declines in sensory functions, including olfaction. The current study was designed to test the hypothesis that cerebral small vessel disease underlies poor olfactory function due to structural declines in brain regions that support olfaction.
Mark A. Eckert, Judy R. Dubno, Zachary M. Soler, Rodney J. Schlosser   +3 more
wiley   +1 more source

Intratympanic dexamethasone microcrystals/lidocaine‐loaded PLGA non‐spherical microparticles for local drug delivery to the inner ear

Animal Models and Experimental Medicine, EarlyView.
Optimized lidocaine‐loaded PLGA non‐spherical particles (LPNMs) and dexamethasone microcrystals (DEX MCs) were prepared. They were then mixed in sodium hyaluronate solution to obtain a co‐delivery system, administrated in guinea pigs to evaluate the pharmacokinetics and biocompatibility of the system.
Dongcheng Wang, Xin Zhang, Zhen Wang, Cheng Ran, Jia Hao, Xiaobo Ma, Minghui Wang, Zhimin Zhou   +7 more
wiley   +1 more source

Cutting‐Edge Advancements in Physical Stimulation for Spiral Ganglion Neuron Protection and Regeneration

Advanced NanoBiomed Research, EarlyView.
Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai, Bin Zhang, Hong Cheng, Yunzhu Huang, Xinyue Han, Yangnan Hu, Renjie Chai, Wei Cao   +7 more
wiley   +1 more source