Results 11 to 20 of about 77,626 (259)
Visualization of macrophage subsets in the development of the fetal human inner ear
Frontiers in Immunology, 2022 BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic trauma or
Claudia Steinacher +11 more
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Current strategies for drug delivery to the inner ear
Acta Pharmaceutica Sinica B, 2013 For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery ...
Hongzhuo Liu, Jinsong Hao, Kevin S. Li
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Potential application value of pigment epithelium-derived factor in sensorineural hearing loss
Frontiers in Neuroscience, 2023 The inner ear is a complex and precise auditory perception system responsible for receiving and converting sound signals into neural signals, enabling us to perceive and understand sound.
Zihui Sun +12 more
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Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration
Nanoscale Research Letters, 2017 Liposome nanocarriers (LPNs) are potentially the future of inner ear therapy due to their high drug loading capacity and efficient uptake in the inner ear after a minimally invasive intratympanic administration.
Jing Zou +4 more
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Journal of Nanobiotechnology, 2010 Background Treatment of inner ear diseases remains a problem because of limited passage through the blood-inner ear barriers and lack of control with the delivery of treatment agents by intravenous or oral administration. As a minimally-invasive approach,
Kinnunen Paavo KJ +6 more
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Gene Delivery into the Inner Ear and Its Clinical Implications for Hearing and Balance
Molecules, 2018 The inner ear contains many types of cell, including sensory hair cells and neurons. If these cells are damaged, they do not regenerate. Inner ear disorders have various etiologies.
Sho Kanzaki
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Nanoparticles in Inner Ear Diseases
National Board of Examinations Journal of Medical Sciences, 2023 Nanoparticles are novel discoveries which hold a promising role for delivering medications into the inner ear in the future. Nanoparticles are formed by the preparation of different biomaterials.
Soumick Ranjan Sahoo
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Multimodal Atlas of the Murine Inner Ear: From Embryo to Adult
Frontiers in Neurology, 2021 The inner ear is a complex organ housed within the petrous bone of the skull. Its intimate relationship with the brain enables the transmission of auditory and vestibular signals via cranial nerves.
Jean-Paul Bryant +15 more
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Otitis media impacts hundreds of mouse middle and inner ear genes. [PDF]
PLoS ONE, 2013 Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken.
Carol J MacArthur +4 more
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NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss
Frontiers in Cell and Developmental Biology, 2022 The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of ...
Francis Rousset +8 more
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