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Editorial: Neuroimmunology of the Inner Ear [PDF]
Frontiers in Neurology, 2021 © 2021 Perin, Marino, Varela-Nieto and Szczepek. Although the term was first officially used in 1982 (1), neuroimmunology is now a mature field that has gained immense traction in the past decade. Thanks to novel technological advances, the cellular and molecular mechanisms that mediate the crosstalk between the immune and nervous systems are ...
Paola Perin +6 more
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The inner ear and the neurologist [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2007 Inner ear disorders are common and patients with vestibular failure often present to a neurology clinic because of their dizziness, gait unsteadiness and oscillopsia. Vestibular disorders can be divided into peripheral and central vestibular disorders.
Michael Gleeson +2 more
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Development of the inner ear [PDF]
Current Opinion in Genetics & Development, 2015 The vertebrate inner ear is a sensory organ of exquisite design and sensitivity. It responds to sound, gravity and movement, serving both auditory (hearing) and vestibular (balance) functions. Almost all cell types of the inner ear, including sensory hair cells, sensory neurons, secretory cells and supporting cells, derive from the otic placode, one of
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Proteomics and the Inner Ear [PDF]
Disease Markers, 2001 The inner ear, one of the most complex organs, contains within its bony shell three sensory systems, the evolutionary oldest gravity receptor system, the three semicircular canals for the detection of angular acceleration, and the auditory system ‐ unrivaled in sensitivity and frequency discrimination.
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Development of a dynamic virtual reality model of the inner ear sensory system as a learning and demonstrating tool [PDF]
, 2009 In order to keep track of the position and motion of our body in space, nature has given us a fascinating and very ingenious organ, the inner ear. Each inner ear includes five biological sensors - three angular and two linear accelerometers - which ...
Gourinat, Yves +2 more
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Inner ear barriers to nanomedicine-augmented drug delivery and imaging
Journal of Otology, 2016 There are several challenges to inner ear drug delivery and imaging due to the existence of tight biological barriers to the target structure and the dense bone surrounding it. Advances in imaging and nanomedicine may provide knowledge for overcoming the
Jing Zou, Ilmari Pyykkö, Jari Hyttinen
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Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture. [PDF]
PLoS ONE, 2016 Stem cell-derived inner ear sensory epithelia are a promising source of tissues for treating patients with hearing loss and dizziness. We recently demonstrated how to generate inner ear sensory epithelia, designated as inner ear organoids, from mouse ...
Rachel E DeJonge +5 more
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Biomedicines, 2021 Zebrafish is an excellent model for exploring the development of the inner ear. Its inner ear has similar functions to that of humans, specifically in the maintenance of hearing and balance. Mafba is a component of the Maf transcription factor family. It
Xiang Chen +10 more
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The endocranial morphology and inner ear of the abelisaurid theropod Aucasaurus garridoi [PDF]
, 2015 A partial cranial endocast and right inner ear of the Cretaceous abelisaurid dinosaur Aucasaurus garridoi were digitally reconstructed from CT scans.
Paulina Carabajal, Ariana +1 more
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Visualization of macrophage subsets in the development of the fetal human inner ear
Frontiers in Immunology, 2022 BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic trauma or
Claudia Steinacher +11 more
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