Results 31 to 40 of about 438,577 (299)

Asymmetrically severe internal auditory canal hypoplasia: A case report. [PDF]

, 2020
We present a case of an otherwise healthy 20-month-old with congenital sensorineural hearing loss. CT and MR imaging demonstrated bilateral asymmetrically severe hypoplasia of the internal auditory canals and vestibulocochlear nerves.
Djalilian, Hamid R, Floriolli, David, Hasso, Anton, Martin, Jeremy W, Senturk, Cagin, Thompson, Matthew, Wishka, Christian   +6 more
core   +1 more source

Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression [PDF]

, 2015
In vertebrates, the inner ear arises from the otic placode, a thickened swathe of ectoderm that invaginates to form the otic vesicle. We report that histone demethylase KDM4B is dynamically expressed during early stages of chick inner ear formation.
Acloque, Ailín L. Buzzi, Alvarez, Baker, Barald, Barembaum, Beyer, Bokoch, Borges, Bradnam, Brown, Brown, Campanero, Chen, Cheng, Christophorou, Cobos, Couture, Deitcher, Driver, Dutton, Emmett, Fodor, Gerchman, Govek, Groves, Hans, Hofmann, Kalari, Kawazu, Lee, Li, Liu, Luo, Majewski, Marianne E. Bronner, Martin, Moro-Balbás, Neves, Pablo H. Strobl-Mazzulla, Park, Represa, Rosa A. Uribe, Sai, Sai, Siegfried, Sims, Stevens, Streit, Strobl-Mazzulla, Tan, Theveneau, Van Kerschaver, Visconti   +53 more
core   +3 more sources

Nanoparticles in Inner Ear Diseases

National Board of Examinations Journal of Medical Sciences, 2023
Nanoparticles are novel discoveries which hold a promising role for delivering medications into the inner ear in the future. Nanoparticles are formed by the preparation of different biomaterials.
Soumick Ranjan Sahoo
doaj   +1 more source

Multimodal Atlas of the Murine Inner Ear: From Embryo to Adult

Frontiers in Neurology, 2021
The inner ear is a complex organ housed within the petrous bone of the skull. Its intimate relationship with the brain enables the transmission of auditory and vestibular signals via cranial nerves.
Jean-Paul Bryant, Vikram Chandrashekhar, Vikram Chandrashekhar, Anthony J. Cappadona, Pashayar P. Lookian, Pashayar P. Lookian, Vibhu Chandrashekhar, Danielle R. Donahue, Jeeva B. Munasinghe, H. Jeffrey Kim, H. Jeffrey Kim, Alexander O. Vortmeyer, John D. Heiss, Zhengping Zhuang, Jared S. Rosenblum, Jared S. Rosenblum   +15 more
doaj   +1 more source

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura, Chicca, Milvia, DANTI, SERENA, Franceschini, Valeria, Martini, Alessandro, Simoni, Edi, Valente, Filippo   +6 more
core   +2 more sources

Precision medicine: a new era for inner ear diseases

Frontiers in Pharmacology
The inner ear is the organ responsible for hearing and balance. Inner ear dysfunction can be the result of infection, trauma, ototoxic drugs, genetic mutation or predisposition. Often, like for Ménière disease, the cause is unknown.
Elisa Tavazzani, Elisa Tavazzani, Paolo Spaiardi, Paolo Spaiardi, Donatella Contini, Giulio Sancini, Giulio Sancini, Giancarlo Russo, Sergio Masetto   +8 more
doaj   +1 more source

Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies

Balkan Medical Journal, 2019
Inner ear anomalies diagnosed using a radiological study are detected in almost 30% of cases with congenital or prelingual-onset sensorineural hearing loss.
Emre Ocak, Duygu Duman, Mustafa Tekin
doaj   +1 more source

Otitis media impacts hundreds of mouse middle and inner ear genes. [PDF]

PLoS ONE, 2013
Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken.
Carol J MacArthur, Fran Hausman, J Beth Kempton, Dongseok Choi, Dennis R Trune   +4 more
doaj   +1 more source

Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography [PDF]

Clinical and Experimental Otorhinolaryngology, 2020
Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic ...
Se-Joon Oh, Il-Woo Lee, Soo-Geun Wang, Soo-Keun Kong, Hong-Ki Kim, Eui-Kyung Goh   +5 more
doaj   +1 more source

Macrophage-related immune responses in inner ear: a potential therapeutic target for sensorineural hearing loss

Frontiers in Neuroscience
Hearing loss is the most common sensory disorder in human beings. Cochlear sensory cells are the basis of hearing. Cochlear sensory cells suffer from various acute or chronic injuries, such as excessive sound stimulation, ototoxic drugs, and age-related ...
Yu-Chen Liu, Kai Xu
doaj   +1 more source