Results 41 to 50 of about 1,188,756 (285)
Nanoparticle-based drug delivery in the inner ear: current challenges, limitations and opportunities
Artificial Cells Nanomedicine and Biotechnology, 2019 Hearing loss is the most common neurosensory impairment worldwide. While conductive hearing loss can be managed by surgery, the management of sensorineural hearing loss (SNHL), related to the damage of sensory cells of the inner ear is more challenging ...
R. Mittal +7 more
semanticscholar +1 more source
The Mechanics of the Inner Ear [PDF]
Nature, 1908 I AM much indebted to Prof. McKendrick for his exceedingly fair review of my monograph on the mechanics of the inner ear (NATURE, June 4, p. 114). One point, however, seems to require a reply on my part. Prof. McKendrick suggests that I should make “a huge model” of the cochlea.
openaire +5 more sources
Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies
Balkan Medical Journal, 2019 Inner ear anomalies diagnosed using a radiological study are detected in almost 30% of cases with congenital or prelingual-onset sensorineural hearing loss.
Emre Ocak, Duygu Duman, Mustafa Tekin
doaj +1 more source
Cells, 2022 Hearing loss affects over 460 million people worldwide and is a major socioeconomic burden. Both genetic and environmental factors (i.e., noise overexposure, ototoxic drug treatment and ageing), promote the irreversible degeneration of cochlear hair ...
Francis Rousset +6 more
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The Human Endolymphatic Sac and Inner Ear Immunity: Macrophage Interaction and Molecular Expression
Frontiers in Immunology, 2019 Background: The endolymphatic sac (ES) is endowed with a multitude of white blood cells that may trap and process antigens that reach the inner ear from nearby infection-prone areas, it thus serves as an immunologic defense organ.
Charlotta Kämpfe Nordström +4 more
semanticscholar +1 more source
Precision medicine: a new era for inner ear diseases
Frontiers in PharmacologyThe inner ear is the organ responsible for hearing and balance. Inner ear dysfunction can be the result of infection, trauma, ototoxic drugs, genetic mutation or predisposition. Often, like for Ménière disease, the cause is unknown.
Elisa Tavazzani +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2019 Hair cells are specialized mechanosensitive cells responsible for mediating balance and hearing within the inner ear. In mammals, hair cells are limited in number and do not regenerate.
Cristiana Mattei +14 more
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Otitis media impacts hundreds of mouse middle and inner ear genes. [PDF]
PLoS ONE, 2013 Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken.
Carol J MacArthur +4 more
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Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography [PDF]
Clinical and Experimental Otorhinolaryngology, 2020 Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic ...
Se-Joon Oh +5 more
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Progenitor Cells from the Adult Human Inner Ear
The Anatomical Record, 2019 Loss of inner ear hair cells leads to incurable balance and hearing disorders because these sensory cells do not effectively regenerate in humans. A potential starting point for therapy would be the stimulation of quiescent progenitor cells within the ...
P. Senn +5 more
semanticscholar +1 more source