Results 51 to 60 of about 1,188,756 (285)

Inner Ear

open access: yes, 2010
Herpes zoster oticus, herpes zoster cephalicus, Ramsay Hunt syndrome.
Arnold, Andreas   +10 more
openaire   +2 more sources

Macrophage-related immune responses in inner ear: a potential therapeutic target for sensorineural hearing loss

open access: yesFrontiers in Neuroscience
Hearing loss is the most common sensory disorder in human beings. Cochlear sensory cells are the basis of hearing. Cochlear sensory cells suffer from various acute or chronic injuries, such as excessive sound stimulation, ototoxic drugs, and age-related ...
Yu-Chen Liu, Kai Xu
doaj   +1 more source

Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss

open access: yesFrontiers in Pharmacology, 2014
Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
doaj   +1 more source

Autoimmune inner ear disease (AIED): A diagnostic challenge

open access: yesInternational Journal of Immunopathology and Pharmacology, 2018
Autoimmune inner ear disease (AIED) has been defined as a condition of bilateral sensorineural hearing loss (SNHL), caused by an ‘uncontrolled’ immune system response.
A. Ciorba   +6 more
semanticscholar   +1 more source

Application of Nanomedicine in Inner Ear Diseases

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
The treatment of inner ear disorders always remains a challenge for researchers. The presence of various physiological barriers, primarily the blood–labyrinth barrier (BLB), limits the accessibility of the inner ear and hinders the efficacy of various ...
Qianyu Lin   +12 more
doaj   +1 more source

Classification and Current Management of Inner Ear Malformations

open access: yesBalkan Medical Journal, 2017
Morphologically congenital sensorineural hearing loss can be investigated under two categories. The majority of congenital hearing loss causes (80%) are membranous malformations. Here, the pathology involves inner ear hair cells.
L. Sennaroğlu, Münir Demir Bajin
semanticscholar   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

open access: yesAdvanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran   +5 more
wiley   +1 more source

Inner ear pathologies impair sodium-regulated ion transport in Meniere’s disease

open access: yesActa Neuropathologica, 2018
Meniere’s disease (MD), a syndromal inner ear disease, is commonly associated with a pathological accumulation of endolymphatic fluid in the inner ear, termed “idiopathic” endolymphatic hydrops (iEH).
Andreas H. Eckhard   +8 more
semanticscholar   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

open access: yesAdvanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso   +5 more
wiley   +1 more source

EARLY STEPS IN INNER EAR DEVELOPMENT: INDUCTION AND MORPHOGENESIS OF THE OTIC PLACODE

open access: yesFrontiers in Pharmacology, 2015
Various cellular replacement therapies using in vitro generated cells to replace damaged tissue have been proposed as strategies to alleviate hearing loss.
Xaiorei eSai, Raj K. Ladher
doaj   +1 more source

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