Results 51 to 60 of about 441,758 (309)

Generation of Vestibular Tissue-Like Organoids From Human Pluripotent Stem Cells Using the Rotary Cell Culture System

open access: yesFrontiers in Cell and Developmental Biology, 2019
Hair cells are specialized mechanosensitive cells responsible for mediating balance and hearing within the inner ear. In mammals, hair cells are limited in number and do not regenerate.
Cristiana Mattei   +14 more
doaj   +1 more source

Otitis media impacts hundreds of mouse middle and inner ear genes. [PDF]

open access: yesPLoS ONE, 2013
Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken.
Carol J MacArthur   +4 more
doaj   +1 more source

WNT Activation and TGFβ-Smad Inhibition Potentiate Stemness of Mammalian Auditory Neuroprogenitors for High-Throughput Generation of Functional Auditory Neurons In Vitro

open access: yesCells, 2022
Hearing loss affects over 460 million people worldwide and is a major socioeconomic burden. Both genetic and environmental factors (i.e., noise overexposure, ototoxic drug treatment and ageing), promote the irreversible degeneration of cochlear hair ...
Francis Rousset   +6 more
doaj   +1 more source

Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2020
Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic ...
Se-Joon Oh   +5 more
doaj   +1 more source

Boundary Distance Loss for Intra-/Extra-meatal Segmentation of Vestibular Schwannoma [PDF]

open access: yes, 2022
Vestibular Schwannoma (VS) typically grows from the inner ear to the brain. It can be separated into two regions, intrameatal and extrameatal respectively corresponding to being inside or outside the inner ear canal. The growth of the extrameatal regions is a key factor that determines the disease management followed by the clinicians.
arxiv   +1 more source

Inner Ear

open access: yes, 2010
Herpes zoster oticus, herpes zoster cephalicus, Ramsay Hunt syndrome.
Arnold, Andreas   +10 more
openaire   +2 more sources

Macrophage-related immune responses in inner ear: a potential therapeutic target for sensorineural hearing loss

open access: yesFrontiers in Neuroscience
Hearing loss is the most common sensory disorder in human beings. Cochlear sensory cells are the basis of hearing. Cochlear sensory cells suffer from various acute or chronic injuries, such as excessive sound stimulation, ototoxic drugs, and age-related ...
Yu-Chen Liu, Kai Xu
doaj   +1 more source

Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss

open access: yesFrontiers in Pharmacology, 2014
Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
doaj   +1 more source

Multifrequency Forcing of a Hopf Oscillator Model of the Inner Ear [PDF]

open access: yes, 2007
In response to a sound stimulus, the inner ear emits sounds called otoacoustic emissions. While the exact mechanism for the production of otoacoustic emissions is not known, active motion of individual hair cells is thought to play a role. Two possible sources for otoacoustic emissions, both localized within individual hair cells, include somatic ...
arxiv   +1 more source

The avian tectorial membrane: Why is it tapered? [PDF]

open access: yesAIP Conf. Proc. 1703, 080005 (2015), 2015
While the mammalian- and the avian inner ears have well defined tonotopic organizations as well as hair cells specialized for motile and sensing roles, the structural organization of the avian ear is different from its mammalian cochlear counterpart. Presumably this difference stems from the difference in the way motile hair cells function.
arxiv   +1 more source

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