Results 81 to 90 of about 434,910 (305)

The Active Traveling Wave in the Cochlea [PDF]

, 2003
A sound stimulus entering the inner ear excites a deformation of the basilar membrane which travels along the cochlea towards the apex. It is well established that this wave-like disturbance is amplified by an active system.
D. D. Greenwood, D. T. Kemp, Frank Jülicher, G. von Békésy, G. Zweig, G. Zweig, H. Duifuis, J. Ashmore, J. Lighthill, J. Zwislocki, L. Robles, P. J. Kolston, T. Gold, Thomas Duke, W. E. Brownell, W. S. Rhode   +15 more
core   +2 more sources

Autonomous Implants

Advanced Materials, EarlyView.
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda, Marcel F. Kunrath, Ling Zhou Zhao, Mahdi Bodaghi, Armin Yousefi, Nureddin Ashammakhi   +5 more
wiley   +1 more source

Connexins and gap junctions in the inner ear - it's not just about K(+) recycling [PDF]

, 2014
Normal development, function and repair of the sensory epithelia in the inner ear are all dependent on gap junctional intercellular communication.
Forge, A, Jagger, DJ
core   +2 more sources

Instrument flight to the inner ear [PDF]

Science Robotics, 2017
Image-guided robotic surgery, designed for operating on small structures, is demonstrated for robotic cochlear implantation.
Stefan Weber, Kate Gavaghan, Wilhelm Wimmer, Tom Williamson, Nicolas Gerber, Juan Anso, Brett Bell, Arne Feldmann, Christoph Rathgeb, Marco Matulic, Manuel Stebinger, Daniel Schneider, Georgios Mantokoudis, Olivier Scheidegger, Franca Wagner, Martin Kompis, Marco Caversaccio   +16 more
openaire   +3 more sources

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa, Alessio Esposito, Giovanni Vozzi, Riccardo Gottardi, Carmelo De Maria   +4 more
wiley   +1 more source

A Degradable Device for Sustainable Capillary Blood Sampling

Advanced Materials Technologies, EarlyView.
The device features a compostable 3D‐printed storage compartment for liquid blood collection and a degradable, poly(ɛ‐caprolactone)‐coated magnesium microneedle patch hidden within a suction cup. Manual compression deploys the MNs, creating small skin punctures, and the subsequent release of compression generates the negative pressure required for ...
Nicole Zoratto, Hanna Krupke, Valeria Mantella, Daniel Gao, David Klein Cerrejon, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Knockout of dhx38 Causes Inner Ear Developmental Defects in Zebrafish

Biomedicines
Background: Alternative splicing is essential for the physiological and pathological development of the inner ear. Disruptions in this process can result in both syndromic and non-syndromic forms of hearing loss.
Mengmeng Ren, Xiang Chen, Liyan Dai, Jiayi Tu, Hualei Hu, Xiaohan Sun, Jiong Luo, Pei Li, Yiyang Fu, Yuejie Zhu, Weiqiang Sun, Zhaohui Tang, Mugen Liu, Xiang Ren, Qunwei Lu   +14 more
doaj   +1 more source

Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors

Nature Communications, 2018
Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here the authors examine human inner ear development by studying key developmental markers and describe organoid cultures from human ...
Marta Roccio, Michael Perny, Megan Ealy, Hans Ruedi Widmer, Stefan Heller, Pascal Senn   +5 more
doaj   +1 more source

LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB)

Signal Transduction and Targeted Therapy, 2022
Inner ear disorders are a cluster of diseases that cause hearing loss in more than 1.5 billion people worldwide. However, the presence of the blood-labyrinth barrier (BLB) on the surface of the inner ear capillaries greatly hinders the effectiveness of ...
Xi Shi, Zihao Wang, Wei Ren, Long Chen, Cong Xu, Menghua Li, Shiyong Fan, Yuru Xu, Mengbing Chen, Fanjun Zheng, Wenyuan Zhang, Xinbo Zhou, Yue Zhang, Shiwei Qiu, Liyuan Wu, Peng Zhou, Xinze Lv, Tianyu Cui, Yuehua Qiao, Hui Zhao, Weiwei Guo, Wei Chen, Song Li, Wu Zhong, Jian Lin, Shiming Yang   +25 more
doaj   +1 more source

Cochlear Implant Outcomes and Genetic Mutations in Children with Ear and Brain Anomalies [PDF]

, 2015
Background. Specific clinical conditions could compromise cochlear implantation outcomes and drastically reduce the chance of an acceptable development of perceptual and linguistic capabilities.
Aimoni, C, Busi, M, Calzolari, F, Castiglione, Alessandro, Granieri, E, Martini, Alessandro, Minazzi, F, Rosignoli, M, Trevisi, Patrizia   +8 more
core   +4 more sources