Results 81 to 90 of about 441,758 (309)

Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing. [PDF]

, 2015
Balance disequilibrium is a significant contributor to falls in the elderly. The most common cause of balance dysfunction is loss of sensory cells from the vestibular sensory epithelia of the inner ear.
Axon, P, Coulson, C, Donnelly, N, Forge, A, Freeman, SR, Irving, R, Jagger, DJ, Lloyd, SK, Moffatt, D, Monksfield, P, Saeed, SR, Taylor, RR, Tysome, J   +12 more
core   +1 more source

Unperceivable Designs of Wearable Electronics

Advanced Materials, EarlyView.
Unperceivable wearable technologies seamlessly integrate into everyone's daily life, for healthcare and Internet‐of‐Things applications. By remaining completely unnoticed both visually and tactilely, by the user and others, they ensure medical privacy and allow natural social interactions.
Yijun Liu, Séverine De Mulatier, Naoji Matsuhisa   +2 more
wiley   +1 more source

Come together over me: Cells that form the dermatocranium and chondrocranium in mice

The Anatomical Record, EarlyView., 2023
Abstract Most bone develops either by intramembranous ossification where bone forms within a soft connective tissue, or by endochondral ossification by way of a cartilage anlagen or model. Bones of the skull can form endochondrally or intramembranously or represent a combination of the two types of ossification.
M. Kathleen Pitirri, Joan T. Richtsmeier, Mizuho Kawasaki, Abigail P. Coupe, Susan Motch Perrine, Kazuhiko Kawasaki   +5 more
wiley   +1 more source

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

Frontiers in Pharmacology
Introduction: One major obstacle in validating drugs for the treatment or prevention of hearing loss is the limited data available on the distribution and concentration of drugs in the human inner ear.
Adele Moatti, Adele Moatti, Shannon Connard, Shannon Connard, Novietta De Britto, Novietta De Britto, William A. Dunn, Srishti Rastogi, Mani Rai, Mani Rai, Lauren V. Schnabel, Lauren V. Schnabel, Frances S. Ligler, Kendall A. Hutson, Douglas C. Fitzpatrick, Alec Salt, Carlton J. Zdanski, Alon Greenbaum, Alon Greenbaum   +18 more
doaj   +1 more source

Asymmetric Inter‐Hemisphere Communication Contributes to Speech Acquisition of Toddlers with Cochlear Implants

Advanced Science, EarlyView.
The present study constructs machine‐learning models to resolve developmental relationships among auditory performance, auditory cortical processing, and functional connectivity of the bilateral language network during the first year of restored hearing. The results demonstrate that asymmetric inter‐hemisphere communication contributes significantly to
Xue Zhao, Meiyun Wu, Haotian Liu, Yuyang Wang, Zhikai Zhang, Yuhe Liu, Yu‐Xuan Zhang   +6 more
wiley   +1 more source

Embryonic cranial cartilage defects in the Fgfr3Y367C/+ mouse model of achondroplasia

The Anatomical Record, EarlyView., 2023
Abstract Achondroplasia, the most common chondrodysplasia in humans, is caused by one of two gain of function mutations localized in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) leading to constitutive activation of FGFR3 and subsequent growth plate cartilage and bone defects.
Susan M. Motch Perrine, Nishchal Sapkota, Kazuhiko Kawasaki, Yejia Zhang, Danny Z. Chen, Mizuho Kawasaki, Emily L. Durham, Yann Heuzé, Laurence Legeai‐Mallet, Joan T. Richtsmeier   +9 more
wiley   +1 more source

Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors

Nature Communications, 2018
Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here the authors examine human inner ear development by studying key developmental markers and describe organoid cultures from human ...
Marta Roccio, Michael Perny, Megan Ealy, Hans Ruedi Widmer, Stefan Heller, Pascal Senn   +5 more
doaj   +1 more source

Probing the Xenopus laevis inner ear transcriptome for biological function

BMC Genomics, 2012
Background The senses of hearing and balance depend upon mechanoreception, a process that originates in the inner ear and shares features across species.
Powers TuShun R, Virk Selene M, Trujillo-Provencio Casilda, Serrano Elba E   +3 more
doaj   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

Cochlear Implant Outcomes and Genetic Mutations in Children with Ear and Brain Anomalies [PDF]

, 2015
Background. Specific clinical conditions could compromise cochlear implantation outcomes and drastically reduce the chance of an acceptable development of perceptual and linguistic capabilities.
Aimoni, C, Busi, M, Calzolari, F, Castiglione, Alessandro, Granieri, E, Martini, Alessandro, Minazzi, F, Rosignoli, M, Trevisi, Patrizia   +8 more
core   +4 more sources