Results 91 to 100 of about 563,854 (280)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Using the Coolest Ae Stars to Constrain Circumstellar Disk Viscosity

The Astrophysical Journal
Classical Ae (CAe) stars are main-sequence, A-type stars with H α emission but no signature of dust. They are thought to be the cool extension of the classical Be stars to lower masses.
R. Anusha, T. A. A. Sigut
doaj   +1 more source

Random Forest Classification of Stars in the Galactic Centre

, 2018
Near-infrared high-angular resolution imaging observations of the Milky Way's nuclear star cluster have revealed all luminous members of the existing stellar population within the central parsec. Generally, these stars are either evolved late-type giants
Plewa, P. M.
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The Birth of Be Star Disks. II. A High-resolution Spectroscopic Campaign and TESS Observations of an Outburst of the Classical Be Star λ Pavonis

The Astrophysical Journal
Be stars are rapidly rotating B stars that have shown emission lines originating in a circumstellar disk. The mechanisms that lead to disk formation and dissipation are not known although progress has been made with some systems.
Sola S. Nova, Noel D. Richardson, Jonathan Labadie-Bartz, Samantha Garcia Flores   +3 more
doaj   +1 more source

Star Formation and Dynamics in the Galactic Centre

, 2015
The centre of our Galaxy is one of the most studied and yet enigmatic places in the Universe. At a distance of about 8 kpc from our Sun, the Galactic centre (GC) is the ideal environment to study the extreme processes that take place in the vicinity of a
A. Ballone, A. Burkert, A. Eckart, A. Eckart, A. Eckart, A. Gualandris, A. Gualandris, A. Gualandris, A. Gualandris, A. Hobbs, A. Krabbe, A. Krabbe, A. Madigan, A. Madigan, A. Mignone, A. Toomre, A.C. Boley, A.C. Boley, A.L. Coil, A.L. Coil, A.M. Ghez, A.M. Ghez, A.M. Ghez, A.M. Ghez, A.M. Ghez, B. Kocsis, B. Paczynski, B. Vollmer, B. Wang, B.-C. Koo, B.C. Bromley, B.M.S. Hansen, C. Alig, C. Alig, C. Hopman, C.M. Telesco, Ch.F. Gammie, D. Downes, D. Haggard, D. Merritt, D. Merritt, D. Merritt, D. Merritt, D. Merritt, D. Pierce-Price, D. Tsiklauri, D.A. Allen, D.C. Lis, D.N.C. Lin, David Merritt, E. Eilon, E. Maoz, E. Pfahl, E. Serabyn, E.A.C. Mills, E.C. Sutton, E.E. Becklin, E.E. Salpeter, E.S. Phinney, F. Antonini, F. Antonini, F. Antonini, F. Eisenhauer, F. Martins, F. Meyer, F. Müller Sánchez, F. Yusef-Zadeh, F. Yusef-Zadeh, F. Yusef-Zadeh, F. Yusef-Zadeh, G. Novak, G. Ponti, G. Witzel, G.F. Rubilar, G.H. Rieke, G.H. Rieke, H. Bartko, H. Bartko, H. Baumgardt, H.B Perets, H.B. Liu, H.B. Liu, H.B. Perets, H.B. Perets, I. Gatley, I. Ginsburg, I. Shlosman, I.A. Bonnell, J. Binney, J. Cuadra, J. Cuadra, J. Cuadra, J. Goodman, J. Guillochon, J. Haas, J. Haas, J. Miralda-Escudé, J. Sanchez-Bermudez, J.-H. Zhao, J.-H. Zhao, J.-M. Huré, J.B. Whiteoak, J.G. Hills, J.G. Hills, J.H. Jeans, J.H. Lacy, J.H. Lacy, J.L. Donovan, J.M. Jackson, J.M. Marr, J.N. Bahcall, J.N. Bahcall, J.R. Goicoechea, J.R. Lu, J.R. Lu, J.W. Haller, J.W. Wadsley, K. Koyama, K. Phifer, K. Sellgren, K.-W. Chan, K.P. Rauch, K.Y. Lo, L. Meyer, L. Yungelson, L. Šubr, L. Šubr, L. Šubr, M. Fujii, M. Fujii, M. Mapelli, M. Mapelli, M. Mapelli, M. Mapelli, M. Montero-Castaño, M. Morris, M. Morris, M. Schartmann, M. Tsuboi, M. Tsuboi, M. Tsuboi, M. Wardle, M.A. Amo-Baladrón, M.C. Miller, M.C.H. Wright, M.H. Christopher, M.J. Reid, M.J. Reid, M.L. Lidov, M.R. Morris, M.T. McGinn, N. Rea, N. Scoville, N.Z. Scoville, O. Agertz, O. Gerhard, O. Pfuhl, P. Amaro-Seoane, P. Côté, P. Kroupa, P. Tamblyn, P.B. Ivanov, P.G. Mezger, P.I. Kolykhalov, P.M. Solomon, P.T.P. Ho, P.T.P. Ho, Ph. Chang, R. Genzel, R. Genzel, R. Genzel, R. Genzel, R. Genzel, R. Genzel, R. Guesten, R. Guesten, R. Schödel, R. Schödel, R. Schödel, R. Schödel, R. Schödel, R. Zylka, R.A. Murray-Clay, R.A. Sunyaev, R.D. Alexander, R.D. Alexander, R.D. Blum, R.D. Blum, R.D. Ekers, R.H. Sanders, R.M. Buchholz, R.M. Herrnstein, R.M. Herrnstein, R.S. McGary, R.V. Shcherbakov, S. Chandrasekhar, S. Chatzopoulos, S. Collin, S. Collin, S. Collin, S. Detweiler, S. Gillessen, S. Gillessen, S. Gillessen, S. Gillessen, S. Gillessen, S. Libonate, S. Martín, S. Nayakshin, S. Nayakshin, S. Nayakshin, S. Nayakshin, S. Portegies Zwart, S. Portegies Zwart, S. Prodan, S. Trippe, S. Yelda, S.K. Okumura, S.S. Kim, S.S. Kim, T. Alexander, T. Do, T. Do, T. Matsubayashi, T. Oka, T. Paumard, T.A. Thompson, T.J.W. Lazio, U. Löckmann, U. Löckmann, U. Löckmann, U. Löckmann, W.E. Lucas, W.R. Brown, W.R.F. Dent, X. Chen, Y. Ao, Y. Clénet, Y. Kozai, Y. Levin, Y.-W. Yu, Y.C. Minh   +241 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Dynamically consistent analysis of Galactic WN4b stars

Astronomy & Astrophysics
Context. Many Wolf-Rayet (WR) stars have optically thick winds that essentially cloak the hydrostatic layers of the underlying star. In these cases, traditional spectral analysis methods are plagued by degeneracies that make it difficult to constrain ...
Lefever R. R., Sander A. A. C., Bernini-Peron M., González-Torà G., Hamann W.-R., Josiek J., Ramachandran V., Schösser E. C., Todt H.   +8 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source