Results 101 to 110 of about 11,496,581 (289)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Spectrophotometry of early type stars

, 1969
A photoelectric spectrum scanner attached to the 16-inch telescope of the Cerro Tololo Inter-American Observatory was used to determine the relative spectral intensity distribution for early type stars. Observations on a minimun of three nights per star have been obtained for about two hundred stars. The tracings extend from 3100 Å to 6000 Å. They were
Gutiérrez-Moreno, A., Moreno, H., Stock, J   +2 more
openaire   +1 more source

Dynamically consistent analysis of Galactic WN4b stars

Astronomy & Astrophysics
Context. Many Wolf-Rayet (WR) stars have optically thick winds that essentially cloak the hydrostatic layers of the underlying star. In these cases, traditional spectral analysis methods are plagued by degeneracies that make it difficult to constrain ...
Lefever R. R., Sander A. A. C., Bernini-Peron M., González-Torà G., Hamann W.-R., Josiek J., Ramachandran V., Schösser E. C., Todt H.   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Spectral energy distributions and colours of hot subluminous stars

Open Astronomy, 2018
Photometric surveys at optical, ultraviolet, and infrared wavelengths provide ever-growing datasets as major surveys proceed. Colour-colour diagrams are useful tools to identify classes of star and provide large samples.
Heber Ulrich, Irrgang Andreas, Schaffenroth Johannes   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Gravity modes and potential evidence for Rossby Waves in late O-type supergiants

Astronomy & Astrophysics
Context. The physical properties of O-type supergiant stars remain largely unexplored. By analysing their light variations, we can sometimes unravel underlying physical phenomena, such as binarity, stellar pulsations, and rotation modes, as well as ...
Cidale Lydia S., Christen Alejandra, Alberici Adam Aldana, Guha Suryani, Lobel Alex, Avila Marín Gunther F., Kraus Michaela, Córsico Alejandro H., Sánchez Arias Julieta P.   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Study of Abundance Patterns in the Sextans and Sculptor Dwarf Spheroidal Galaxies

The Astrophysical Journal
In this work, we employ a multicomponent decomposition model to study the Sextans and Sculptor dwarf spheroidal galaxies, which have distinct evolutionary histories.
Shuaishuai Yang, Shichao Zhang, Lu Zhang, Hongjie Li   +3 more
doaj   +1 more source

Quantitative spectroscopy of single and multiple OB-type stars

Astronomy & Astrophysics
Aims. The plethora of spectra of OB-type stars in observatory archives and the much larger numbers to come from the WEAVE and 4MOST spectroscopic facilities require efficient, but also accurate and precise methods for (semi)automatic quantitative ...
Aschenbrenner P., Przybilla N.
doaj   +1 more source