Results 121 to 130 of about 40,670 (264)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Probable nonradial g-mode pulsation in early A-type stars
, 2006 Aims. Asteroseismology of early A-type stars could be a new tool to test stellar convection theories. Methods. A survey for line profile variability in early A-type stars has been performed in order to detect nonradial pulsation signatures. Results.
Antonello E. +3 more
core +2 more sources
A Spectroscopic Survey of Metal-poor OB Stars in Local Dwarf Galaxy NGC 3109
The Astrophysical JournalAs JWST uncovers increasingly strong evidence that metal-poor, massive stars in early galaxies dominated reionization, observational constraints on the properties of such stars are more relevant than ever before.
Abby Mintz +5 more
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Equilibria and oscillations of magnetised neutron stars
, 2010 We investigate equilibrium configurations and oscillation spectra of neutron stars,modelled as rotating magnetised fluid bodies in Newtonian gravity. We also explorethe idea that these model neutron stars could have dynamics analogous to rigid-bodyfree ...
Lander, Samuel Kenneth
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Doppler imaging of young solar-type stars using the ANU 2.3 m Siding Spring Telescope [PDF]
, 2013 The study of surface activity on young solar-type stars provides an opportunity to improve understanding of stellar dynamos and indirectly gain insight into early solar evolution.
Burton, Donna Marie
core
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source