Results 71 to 80 of about 1,784,584 (391)

Shifting to Remote Learning During COVID-19: Differences for Early Childhood and Early Childhood Special Education Teachers

Early Childhood Education Journal, 2021
This study explored similarities and differences in how early childhood education (ECE) teachers (n = 947) and early childhood special education (ECSE) teachers (n = 160) provided remote learning to young children and their families following COVID-19 ...
E. Steed, N. Leech
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Relationship between static and dynamic balance in 4-to-5-year-old preschoolers: a cross-sectional study

BMC Pediatrics
Background Balance is crucial for physical development in preschool children. Exploring the relationship between different types of balance can help understand early physical development in children.
Ruqiang Liu, Juan Yang, Feifei Xi, Zichun Xu   +3 more
doaj   +1 more source

Effective Early Childhood Programmes [PDF]

, 2009
Published in collaboration with the Open University, Early Childhood in Focus offers accessible and clear reviews of the best and most recent available research, information and analysis on key policy issues, offering clear messages on core policy topics
Siraj-Blatchford, Iram, Woodhead, Martin
core  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Assessing the role of parent-child conflict and closeness in children’s depression: insights from a meta-analysis

Child and Adolescent Psychiatry and Mental Health
Depression, as a prevalent public health concern, has long been the focus of research attention. However, the magnitude and moderating mechanisms underlying the association between parent–child relationships and childhood depression remain inconclusive ...
Juanjuan Sun, Yuling Yin, Jinghui Zhang, Yan Li   +3 more
doaj   +1 more source

Multicultural Curriculum in Rural Early Childhood Programs

, 2015
This study investigated the use of multicultural curricula in early childhood programs (licensed and licensed-exempt) in rural communities in Wyoming.
Nganga, Lydiah, Dr.
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The impact of maternal parenting stress on early childhood development: the mediating role of maternal depression and the moderating effect of family resilience

BMC Psychology
Objective Early childhood is a critical stage of rapid cognitive, social, emotional, and physical development. The development during this period is crucial for the long-term health and well-being of children.
Baocheng Pan, Yizhao Gong, Youli Wang, Jiaxuan Miao, Chengli Zhao, Yan Li   +5 more
doaj   +1 more source