Results 121 to 130 of about 185,568 (314)

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

open access: yesAdvanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr   +6 more
wiley   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

The organization of early care in early childhood education

open access: yesTendencias Pedagógicas, 2015
Nowadays the school faces a great challenge to be able to pay attention to every child in the early stages of education. These chaHenges are basically the early schooling of children and a schooling which includes ALL the children. The idea of integration (inclusion in this case) has been something real in the early stages at school.
Rosalía Aranda Redruello   +1 more
openaire   +1 more source

Intersecting vulnerabilities: factors contributing to pregnancy among learners with disabilities in two Namibian resource schools

open access: yesCogent Education
Learners with disabilities face compounded vulnerabilities that increase their risk of pregnancy while at school. Yet, research on the factors contributing to learner pregnancy in Namibian resource schools remains scarce.
Zelda J. Kandiimuine, Rauna K. Haitembu
doaj   +1 more source

Early childhood education and care for sustainability : Historical context and current challenges

open access: yes, 2017
It is widely acknowledged that social, economic, environmental and political challenges are affecting young children’s lives all over the world. This chapter discusses Early Childhood Education and Care for Sustainability (ECECfS) from two perspectives ...
Samuelsson, I. P.,   +1 more
core  

Access to early childhood education in Australia: insights from a qualitative study [PDF]

open access: yes, 2014
Based on interviews with 94 parents in Victoria, South Australia, Tasmania, and Western Australia, this report investigates parents\u27 knowledge of and attitudes towards early childhood education. Executive summary This report documents the background,
Rhys Price-Robertson   +4 more
core  

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

open access: yesAdvanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng   +16 more
wiley   +1 more source

Factors influencing music teaching among primary and early childhood education and care generalist teachers: a meta-narrative review

open access: yesFrontiers in Education
A growing body of research has explored factors influencing music teaching among pre-service and in-service generalist teachers in primary and early childhood education and care (ECEC).
Thomas Nguyen   +4 more
doaj   +1 more source

Early childhood safety education: An overview of safety curriculum in outer metropolitan, regional and rural NSW

open access: yes, 2009
This article reports on preliminary findings from a 2008 survey and telephone interviews with 27 directors of early childhood education and care (ECEC) services located in regional and rural districts of the Australian state of New South Wales. Data from
Saltmarsh, Sue   +2 more
core   +1 more source

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