Results 121 to 130 of about 859,028 (310)

The organization of early care in early childhood education

Tendencias Pedagógicas, 2015
Nowadays the school faces a great challenge to be able to pay attention to every child in the early stages of education. These chaHenges are basically the early schooling of children and a schooling which includes ALL the children. The idea of integration (inclusion in this case) has been something real in the early stages at school.
Rosalía Aranda Redruello, Carmen de Andrés Viloria   +1 more
openaire   +1 more source

YHDESSÄ JA SAMAAN SUUNTAAN : Kasvatuskumppanuus Vaahteramäen päiväkodissa [PDF]

, 2010
Tutkimuksen aiheena oli kasvatuskumppanuus siihen erityisesti panostavassa varhaiskasvatusyksikössä. Tarkoitus oli mallintaa hyväksi havaittuja työmuotoja kasvatuskumppanuuden osalta.
Eskonen-Myllylä, Taru, Saarela, Heli
core  

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

Advanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo, Zhiqing Zhao, Wei Wang, Jianfang Niu, Bing Wang, Yunfei Lin, Wei Guo, Taiqiang Yan   +7 more
wiley   +1 more source

Portrayals of special educational needs in Norwegian ECEC psychoeducational reports: a document analysis in the context of inclusion

Frontiers in Education
IntroductionThis study aims to contribute to the ongoing debate on promoting more inclusive assessment practices for children in need of special educational support.
Agnete Kristiansen, Agnete Kristiansen, Marit Uthus   +2 more
doaj   +1 more source

Early Childhood Education and Care [PDF]

Research in Comparative and International Education, 2008
Ailie Cleghorn, Larry Prochner
openaire   +1 more source

Children's Early Learning: What the state of Missouri can do [PDF]

, 2002
Includes bibliographical references.Findings from the Midwest Child Care Research Consortium indicate early childhood education settings are of low quality in three areas that are key to early learning: Learning Activities, Language and Reasoning and ...
Mayfield, Wayne A. (Wayne Andrew), 1966-, Scott, Jacqueline L., 1963-, Thornburg, Kathy R.   +2 more
core  

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

How to encourage empathy from birth: neurological roots and the importance of responsive practice [PDF]

, 2017
Studies in social neuroscience and brain imaging that have investigated the neural basis of human empathy reveal that the development of empathy is rooted in early infancy, well before the emergence of verbal abilities and more complex capacities in
French, Geraldine
core  

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Crisis management in distance education in the age of artificial intelligence: opportunities, challenges and ethical dimensions

Frontiers in Education
This paper examines the role of Artificial Intelligence (AI) in crisis management within distance education, focusing on the technological, organizational, and social challenges that became particularly evident during the COVID-19 pandemic.
Fotini Kyrou, Panagiotis Vergis, Georgia Rogari, Anna Saiti, Evangelia Manousou   +4 more
doaj   +1 more source