Results 121 to 130 of about 1,409,842 (340)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Implementation of an electronic health information system using DHIS2 tracker to manage and evaluate the National cervical screening programme in Bangladesh

BMC Public Health
Background The cervical screening programme in Bangladesh upgraded its electronic health information system (e-HIS) in 2019 using DHIS2 tracker application. The upgraded e-HIS collects individual level data and has useful functionalities like sending SMS
Ashrafun Nessa, Shekh Md Nazim Uddin, Eric Lucas, Pradip Nag, Sathishrajaa Palaniraja, Maryluz Rol, Md. Abdus Salam Khan, Muhammad Abdul Hannan Khan, Shirin Akter Begum, Romena Afroz, Noor E Ferdous, Richard Muwonge, Partha Basu   +12 more
doaj   +1 more source

Mucins as Potential Biomarkers for Early Detection of Cancer. [PDF]

Cancers (Basel), 2023
Gautam SK, Khan P, Natarajan G, Atri P, Aithal A, Ganti AK, Batra SK, Nasser MW, Jain M.   +8 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Contribution of pks+ Escherichia coli (E. coli) to Colon Carcinogenesis

Microorganisms
Colorectal cancer (CRC) stands as a significant global health concern, ranking second in mortality and third in frequency among cancers worldwide. While only a small fraction of CRC cases can be attributed to inherited genetic mutations, the majority ...
Mohammad Sadeghi, Denis Mestivier, Iradj Sobhani   +2 more
doaj   +1 more source

Development of New Diagnostic Methods for Early Detection of Cancer: Integration of Genomic and Bioinformatics Technologies

, 2023
Yelfi Anwar, Anisa Almahira, Neneng Nurfitria, Rizaldy Saputra, Putra Rizki Said   +4 more
openalex   +2 more sources

What Is Differences between Medical Imaging Modalities for Assessment of the Breast [PDF]

Breast cancer is the most common female cancer with more than 45,000 cases diagnosed per annum in the UK. Early detection of breast cancer is associated with improved survival. There are several imaging modalities for assessment of the breast.
بهروزكيا, ژاله, حدادی, غلامحسن, رفاهی, سهیلا   +2 more
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Breast cancer treatment and its impact on survival in Morocco: a study over a decade

BMC Cancer
Background In Morocco, much progress has been made in breast cancer treatment. However, there is limited information on survival outcomes of breast cancer patients according to their therapeutic management.
Hind Mrabti, Catherine Sauvaget, Karima Bendahhou, Farida Selmouni, Richard Muwonge, Eric Lucas, Youssef Chami, Maria Bennani, Hassan Errihani, Abdellatif Benider, Rachid Bekkali, Partha Basu   +11 more
doaj   +1 more source

Low Frequency of 185delAG Founder Mutation of BRCA1 Gene in Iranian Breast Cancer Patients [PDF]

AIM: The mutations in two breast cancer susceptibility genes, BRCA1 and BRCA2, are frequently associated with familial breast cancer. In this study, we aimed to investigate the probable founder mutations of BRCA1 and BRCA2 genes in Iranian breast ...
الوندی, احسان, حبیبی, لاله, حسینی اصل, سید سعید, صوابی, آرزو, عطری, مرتضی, مهدی پور, پروین   +5 more
core