Results 141 to 150 of about 1,409,842 (340)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Impact of early detection on cancer curability: A modified Delphi panel study. [PDF]

PLoS One, 2022
Schwartzberg L, Broder MS, Ailawadhi S, Beltran H, Blakely LJ, Budd GT, Carr L, Cecchini M, Cobb P, Kansal A, Kim A, Monk BJ, Wong DJ, Campos C, Yermilov I.   +14 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Evaluation of Usability and User Experience of Oncodoc 's M-Health Application for Early Detection of Cancer. [PDF]

Asian Pac J Cancer Prev, 2022
Wulandari R, Pangarsa EA, Andono PN, Rachmani E, Sidiq M, Setyowati M, Waluyo DE.   +6 more
europepmc   +1 more source

Early detection of pancreatic cancer

World Journal of Clinical Cases
The diagnosis of pancreatic cancer associates an appalling significance. Detection of preinvasive stage of pancreatic cancer will ameliorate the survival of this deadly disease. Premalignant lesions such as Intraductal Papillary Mucinous Neoplasms or Mucinous Cystic Neoplasms of the pancreas are detectable on imaging exams and this permits their ...
openaire   +2 more sources

Advances in Optical Aptasensors for Early Detection and Diagnosis of Various Cancer Types [PDF]

, 2021
Qurat ul ain Zahra, Qaiser Ali Khan, Zhaofeng Luo   +2 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Toward universal immunofluorescence normalization for multiplex tissue imaging with UniFORM

Cell Reports: Methods
Summary: We present UniFORM, a non-parametric, Python-based pipeline for normalizing multiplex tissue imaging (MTI) data at both the feature and pixel levels.
Kunlun Wang, Kaoutar Ait-Ahmad, Sam Kupp, Zachary Sims, Eric Cramer, Zeynep Sayar, Jessica Yu, Melissa H. Wong, Gordon B. Mills, S. Ece Eksi, Young Hwan Chang   +10 more
doaj   +1 more source

The recent advancements in the early detection of cancer biomarkers by DNAzyme-assisted aptasensors. [PDF]

J Nanobiotechnology, 2022
Kamali H, Golmohammadzadeh S, Zare H, Nosrati R, Fereidouni M, Safarpour H.   +5 more
europepmc   +1 more source

APPLICATIONS OF TISSUE DOPPLER AND SPECKLE TRACKING ECHOCARDIOGRAPHY IN THE EARLY DETECTION OF DIASTOLIC DYSFUNCTION IN CANCER PATIENTS UNDERGOING ANTHRACYCLINEBASED CHEMOTHERAPY

, 2018
Chaithra Nayak, Pai Narasimha D, Padmakumar Ramachandran, Udupa Karthik S, Umesh Pai, Monteiro Francis N. P.   +5 more
openalex   +1 more source