Results 21 to 30 of about 3,779,020 (301)

Macrolide Therapy in Chronic Inflammatory Diseases

open access: yesMediators of Inflammation, 2012
Macrolides are a group of antibiotics with a distinctive macrocyclic lactone ring combined with sugars (cladinose, desosamine). The action of macrolides is to block protein synthesis by binding to the subunit of 50S ribosome of bacteria.
Brygida Kwiatkowska, Maria Maślińska
doaj   +1 more source

A Novel Model Based on Genomic Instability-Associated Long Non-Coding RNAs for Predicting Prognosis and Response to Immunotherapy in Patients With Lung Adenocarcinoma

open access: yesFrontiers in Genetics, 2021
Background: Emerging scientific evidence has shown that long non-coding RNAs (lncRNAs) exert critical roles in genomic instability (GI), which is considered a hallmark of cancer. To date, the prognostic value of GI-associated lncRNAs (GI-lncRNAs) remains
Guangxu Tu   +17 more
doaj   +1 more source

Analyzing the Triad Diagnosis Requirement for Autism in Arkansas [PDF]

open access: yes, 2020
Autism Spectrum Disorder (ASD) is a developmental disorder that has steadily increased in incidence and prevalence over the last ten years. While the disorder can be diagnosed as early as two years of age, most children do not receive a diagnosis until ...
Barrientos-Figueroa, Liliana
core   +2 more sources

A next-generation sequencing approach to identify gene mutations in early-and late-onset hypertrophic cardiomyopathy patients of an Italian cohort [PDF]

open access: yes, 2016
Sequencing of sarcomere protein genes in patients fulfilling the clinical diagnostic criteria for hypertrophic cardiomyopathy (HCM) identifies a disease-causing mutation in 35% to 60% of cases.
Autore, Camillo   +11 more
core   +1 more source

Adjuvant chemotherapy may improve long-term outcomes in stage IB non-small cell lung cancer patients with previous malignancies: A propensity score-matched analysis

open access: yesFrontiers in Oncology, 2022
BackgroundRoutine administration of adjuvant chemotherapy for stage IB non-small cell lung cancer (NSCLC) remains controversial. To our knowledge, no available studies have assessed the outcomes of chemotherapy in patients with stage IB NSCLC who had ...
Ke Zhou   +12 more
doaj   +1 more source

Novel spectral kurtosis technology for adaptive vibration condition monitoring of multi-stage gearboxes [PDF]

open access: yes, 2016
In this paper, the novel wavelet spectral kurtosis (WSK) technique is applied for the early diagnosis of gear tooth faults. Two variants of the wavelet spectral kurtosis technique, called variable resolution WSK and constant resolution WSK, are ...
Barbieri, M.   +5 more
core   +1 more source

Early Diagnosis and Treatment [PDF]

open access: yesDeutsches Ärzteblatt international, 2014
Congratulations to the authors for choosing this important topic (1). As shown in their review, regeneration after nerve reconstruction is by no means guaranteed (1), in particular not in older patients (2). The most common nerve injury – damage to the median nerve during carpal tunnel surgery (1) – often occurs in middle-aged/ older patients where the
Frank, Unglaub   +2 more
openaire   +2 more sources

Early diagnosis of cancer [PDF]

open access: yes, 1974
This paper was read at a symposium held at the Royal University of Malta on the 21st March 1974 organised by the Association of Surgeons and Physicians of Malta. Particular data on the incidence of the various forms of malignancies in the Maltese Islands
Sultana, H.M.
core   +1 more source

Prognostic role of the platelet to lymphocyte ratio (PLR) in the clinical outcomes of patients with advanced lung cancer receiving immunotherapy: A systematic review and meta-analysis

open access: yesFrontiers in Oncology, 2022
BackgroundIt remains controversial whether the platelet to lymphocyte ratio (PLR) serves as a potential indicator for the efficacy of immunotherapy in advanced lung cancer.
Ke Zhou   +13 more
doaj   +1 more source

Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]

open access: yes, 2017
Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla   +12 more
core   +4 more sources

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