Results 61 to 70 of about 136,179 (257)

Mapping data gaps to estimate biomass across Brazilian Amazon forests

Forest Ecosystems, 2020
Background Tropical forests play a fundamental role in the provision of diverse ecosystem services, such as biodiversity, climate and air quality regulation, freshwater provision, carbon cycling, agricultural support and culture.
Graciela Tejada, Eric Bastos Görgens, Alex Ovando, Jean Pierre Ometto   +3 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Sanukitoid stable isotopes reveal complex crust-mantle dynamics in the early Earth

Communications Earth & Environment
The Archean to Paleoproterozoic Earth underwent significant changes in surface, crust and mantle systems, yet interactions between these reservoirs remain poorly constrained.
Ren-Zhi Zhu, Mike Fowler, Jiyuan Yin, Fang Huang, Robert H. Smithies, Laura M. Spencer, Marc-Alban Millet, Hugo Moreira, Craig Storey, Henrique Bruno, Kumar Batuk Joshi, Xiaoping Long, Shaocong Lai, Guochun Zhao   +13 more
doaj   +1 more source

Spatiotemporal dynamics and optimization of water quality assessment in the Nantong section of the Yangtze River Basin: A WQImin approach

Journal of Hydrology: Regional Studies
Study region: The Yangtze River within the Nantong region, Jiangsu Province, China Study focus: This study investigates the spatiotemporal dynamics of water quality in the Nantong section of the Yangtze River Basin. It focuses on developing a novel water
Weifeng Xiao, Bozhi Ren, Bai Wu, Xinping Deng   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Extreme Drought Events over Brazil from 2011 to 2019

Atmosphere, 2019
Drought-related disasters are among the natural disasters that are able to cause large economic and social losses. In recent years, droughts have affected different regions of Brazil, impacting water, food, and energy security. In this study, we used the
Ana Paula M. A. Cunha, Marcelo Zeri, Karinne Deusdará Leal, Lidiane Costa, Luz Adriana Cuartas, José Antônio Marengo, Javier Tomasella, Rita Marcia Vieira, Alexandre Augusto Barbosa, Christopher Cunningham, João Victor Cal Garcia, Elisangela Broedel, Regina Alvalá, Germano Ribeiro-Neto   +13 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Associations between the 2022 global mpox outbreak and multifaceted factors: A multi-geographical retrospective study

One Health
Unlike prior travel-related mpox cases, the 2022 outbreak of mpox virus (MPXV) clade IIb outside endemic regions posed a significant global health threat.
Yuxi Ge, Yifei Wang, Ziqin Zhou, Zhirui Zhang, Yunyu Tian, Yun Feng, Peiyi Wu, Yuxin Wang, Ziyan Liu, Bingying Li, Zengmiao Wang   +10 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source