Results 261 to 270 of about 920,236 (292)

Early life stress and metabolism

Current Opinion in Behavioral Sciences, 2019
Exposure to stress is a normal and constant facet of life. However, excessive or chronic stress at particular phases of brain development can have lasting detrimental effects on many aspects of physiology, including appetite regulation and metabolism. A specific window of vulnerability to the lasting effects of stress is the early life period, in utero
Sajida Malik, Sarah J Spencer
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Early life stress and cortisol: A meta-analysis

Hormones and Behavior, 2018
Given the high prevalence of early life stress (ELS) and the potential physiological dysregulation such experiences can lead to, this meta-analysis tested the relationship between ELS and cortisol. Search terms related to ELS and cortisol were entered in to PsycINFO and PubMed. Effect sizes were extracted for four outcomes variables: cortisol awakening
Nia, Fogelman, Turhan, Canli
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Early life stress in depression susceptibility

Science, 2017
Neurodevelopment The linkage between stress early in life and behavioral depression in adulthood is complex. Pena et al. were able to define a time period in early development when mice are especially susceptible to stress. Mice subjected to stress during this time period were less resilient to stress in adulthood.
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Plasticity of the epigenome during early-life stress

Seminars in Cell & Developmental Biology, 2018
Early life adversity remains a significant risk factor for the development of a host of negative behavioural and pathological outcomes in adulthood long after the stressor is over. Recent evidence indicates that these lasting effects of ELS may occur via alterations in the epigenetic landscape.
Burns, S. Barnett, Szyszkowicz, J. Kasia, Luheshi, Giamal, Lutz, Pierre-Eric, Turecki, Gustavo   +4 more
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Stress in early life inhibits neurogenesis in adulthood

Trends in Neurosciences, 2005
Both structure and function of the hippocampus are altered by stress: by increasing levels of corticosteroids, stress causes atrophy of CA3 pyramidal cell dendrites, inhibits adult neurogenesis in the dentate gyrus, and impairs hippocampus-dependent learning.
Yashmin J G, Karten, Ana, Olariu, Heather A, Cameron   +2 more
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Early Life Stress and Psychopathology

2018
Exposure to chronic or severe stressful life events during childhood and adolescence—frequently referred to as early life stress (ELS) or childhood adversity—has powerful and lasting associations with psychopathology across the life course. This chapter reviews the growing body of research on ELS and psychopathology across the life course, with a ...
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The Kindling/Sensitization Model and Early Life Stress

2020
Few animal models address the characteristics of the longitudinal course of bipolar disorder. However, behavioral sensitization (to recurrent stressors and psychomotor stimulants) and kindling of seizures both provide clues to mechanisms in the progressive course of bipolar disorder.We describe aspects of bipolar illness that show sensitization and ...
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Early Adolescence as a Life Stress

1980
Relationships between life stress and susceptibility to various physical and psychological disorders has been shown by many studies. These issues deserve careful study in early adolescence in particular. The concept of early adolescence is relatively new.
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Effects Of Stress In Early Life

2004
Abstract International adoptees encounter stress both prenatally and postnatally (Table 8–1). Most are products of unwanted pregnancies. After birth, many suffer from abandonment, institutionalization, malnutrition, recurrent illnesses, environmental deprivation, and/or emotional neglect.
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Methods for Modeling Early Life Stress in Rodents

Animal models of early life stress/adversity (ELS) have provided a foundation from which our understanding of the psychoneuroimmunology of childhood trauma has expanded over recent decades. Rodent models are a cornerstone of the ELS literature with many studies utilizing paradigms based on early life separation/deprivation protocols and manipulating ...
Jamie Y, Choe, Harlan P, Jones
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