Results 71 to 80 of about 1,814,700 (309)
Managing Invasive Species: How Much Do We Spend? [PDF]
, 2012 Invasive species: they’re along roadways and up mountain trails; they’re in lakes and along the coast; chances are they’re in your yard. You might not recognize them for what they are—plants or animals not native to Alaska, brought here accidentally or
Alaska SeaLife Center +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Social Enterprise: A Portrait of the Field [PDF]
, 2010 The Social Enterprise Alliance recently partnered with Community Wealth Ventures and Duke University's Center for the Advancement of Social Entrepreneurship to assess the state of social enterprise in the nonprofit sector in the United States and Canada.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Bolder Together 2: Building Grassroots Movements for Change [PDF]
, 2016 California's demographics are changing fast, but rates of voting and civic participation haven't kept up. In four rapidly growing counties across the state, a group of funders is working with local organizations to support diverse communities to lift up ...
Cathy Cha, William H. Woodwell, Jr.
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Agricultural Seasonality and the Organization of Manufacturing During Early Industrialization: The Contrast Between Britain and the United States [PDF]
, 1991 The United States differed dramatically from Britain in the way manufacturing was organized during early industrialization. Even before widespread mechanization, American production was almost exclusively from centralized plants, whereas the British and other European economies were characterized by extensive cottage manufacture. This paper argues that
Kenneth L. Sokoloff, David Dollar
openaire +2 more sources
Co-Creation: Viewing Partnerships Through A New Lens [PDF]
, 2016 Collaboration remains an on-going discourse throughout the funder community, but little has been written about explorations or innovations into different ways of working collectively, beyond what was established decades ago.The Connecticut legislation ...
Patricia Bowie
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Conflict Prevention, Management, and Resolution: Africa — Regional Strategies for the Prevention of Displacement and Protection of Displaced Persons: The Cases of the OAU, ECOWAS, SADC, and IGAD [PDF]
, 2001 This Article seeks to examine the preparedness of certain African regional actors to protect displaced persons in times of armed conflict, and to prescribe formulas to strengthen the capabilities of such actors.
Levitt, Jeremy
core +3 more sources