Results 71 to 80 of about 985,100 (309)

VEWS: A Wikipedia Vandal Early Warning System

open access: yes, 2015
We study the problem of detecting vandals on Wikipedia before any human or known vandalism detection system reports flagging potential vandals so that such users can be presented early to Wikipedia administrators.
Kumar, Srijan   +2 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Early warning systems [PDF]

open access: yes
Banks and banking ; Bank supervision ; Problem ...
Mark E. Levonian
core  

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Comparing early warning systems for banking crises [PDF]

open access: yes, 2007
Despite the extensive literature on prediction of banking crises by Early Warning Systems (EWS), their practical use by policy makers is limited, even in the international financial institutions.
Davis, EP, Karim, D
core  

An Early Warning System for Asteroid Impact

open access: yes, 2010
Earth is bombarded by meteors, occasionally by one large enough to cause a significant explosion and possible loss of life. Although the odds of a deadly asteroid strike in the next century are low, the most likely impact is by a relatively small ...
Tonry, John L.
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Sparse Bayesian learning-based mainlobe blanket jamming suppression algorithm

open access: yesThe Journal of Engineering, 2019
The suppression of mainlobe jamming (MLJ) is a hard task and an open problem in the electronic counter-countermeasures field. In this article, a sparse Bayesian learning (SBL)-based mainlobe blanket jamming suppression algorithm is proposed for solving ...
Bilei Zhou   +4 more
doaj   +1 more source

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