Results 61 to 70 of about 985,100 (309)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clutter Suppression Approach for End-Fire Array Airborne Radar Based on Adaptive Segmentation

open access: yesIEEE Access, 2019
End-fire array antenna is a kind of special radar antenna with beam pointing perpendicular to the normal direction of the array. Because of its low profile and directional radiation characteristics, it is especially suitable for blind zone compensation ...
Yongwei Li   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Bi-level JOMP for DOA estimation in coprime array with off-grid targets

open access: yesThe Journal of Engineering, 2019
The direction of arrival (DOA) estimation for off-grid targets in the coprime array, which can extend degrees of freedom, is studied. Among existing research results, joint orthogonal matching pursuit (JOMP) has obvious advantages in complexity, but ...
Ying Jiang   +4 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Few‐label aerial target intention recognition based on self‐supervised contrastive learning

open access: yesIET Radar, Sonar & Navigation
Identifying the intentions of aerial targets is crucial for air situation understanding and decision making. Deep learning, with its powerful feature learning and representation capability, has become a key means to achieve higher performance in aerial ...
Zihao Song   +5 more
doaj   +1 more source

Joint azimuth-range jamming for ISAR based on time delay

open access: yesThe Journal of Engineering, 2019
Aiming at the problem that azimuth cosinusoidal phase-modulation cannot be directly implemented in application, and two-dimensional modulation can only be carried out in azimuth and distance, respectively, a joint azimuth-range jamming method based on ...
Li Botao   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Index for task scheduling in phased array radar

open access: yesThe Journal of Engineering, 2019
In the task scheduling problem of phased array radar, the objective function is usually based on the time shifting rate (TSR). However, the TSR cannot achieve expected scheduling performance in non-linear filtering systems.
Yi Duan   +3 more
doaj   +1 more source

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