Results 51 to 60 of about 96,718 (306)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Inclusive early warning early action: Checklist and implementation guide [PDF]
, 2023 The checklist and implementation guide for inclusive early warning and early action was developed as part of the Climate Risk and Early Warning Systems (CREWS) Pacific initiative and seeks to contribute to the implementation of the Executive Action Plan ...
Kelman, Ilan, Fearnley, Carina
core
Automatic early warning systems for the environment [PDF]
Nuclear Technology and Radiation Protection, 2003 Computerized, continuous monitoring environmental early warning systems are complex networks that merge measurements with the information technology. Accuracy, consistency, reliability and data quality are their most important features.
Lesjak Martin
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Translating Warnings into Action – How We Can Improve Early Warning Systems to Protect Communities [PDF]
, 2023 Early warnings for hazards are essential for living safely and minimising economic losses. For many hazards, it is possible to give advance notice and accurate information to help communities prepare and respond. However, issuance of the warning itself
Kelman, Ilan +2 more
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Early warning systems for malaria in Africa: from blueprint to practice.
, 2007 Although the development of early warning systems for malaria has been advocated by international agencies and academic researchers for many years, practical progress in this area has been relatively modest. In two recent articles, Thomson et al. provide
Abeku, Tarekegn A, Cox, Jonathan
core +1 more source
Experiences from site-specific landslide early warning systems [PDF]
Natural Hazards and Earth System Sciences, 2013 Landslide early warning systems (EWSs) have to be implemented in areas with large risk for populations or infrastructures when classical structural remediation measures cannot be set up.
C. Michoud +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source