Results 61 to 70 of about 82,066 (257)

AN EARLY WARNING SYSTEM FOR FLOUNDER DISEASE [PDF]

, 2009
With the constant expansion of the scale and mismanagement in aquaculture,the diseases of flounder occur more and more frequently than before, which has brought great economic losses to fish farmers. For the sake of the problem described above, based on a great number of surveys, the early warning theory of flounder disease, the analysis of the ...
Bin Xing, Daoliang Li, Jianqin Wang, Qingling Duan, Jiwen Wen   +4 more
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Lessons learned from flash floods early warning system in a mountainous rur-urban region of Colombia

Environmental Challenges
The city of Manizales, Colombia, located in the tropical Andes, faces recurrent hydroclimatological risks due to its mountainous terrain, high rainfall variability, and urban expansion into vulnerable areas.
Cristhian Camilo Luna, Jeannette Zambrano Nájera, Jorge Julián Vélez Upegui   +2 more
doaj   +1 more source

The effectiveness of physiologically based early warning or track and trigger systems after triage in adult patients presenting to emergency departments: a systematic review

BMC Emergency Medicine, 2017
Background Changes to physiological parameters precede deterioration of ill patients. Early warning and track and trigger systems (TTS) use routine physiological measurements with pre-specified thresholds to identify deteriorating patients and trigger ...
Francesca Wuytack, Pauline Meskell, Aislinn Conway, Fiona McDaid, Nancy Santesso, Fergal G. Hickey, Paddy Gillespie, Adam J. N. Raymakers, Valerie Smith, Declan Devane   +9 more
doaj   +1 more source

SNEWS: the SuperNova Early Warning System

New Journal of Physics, 2004
25 pages, for New Journal of Physics Focus Issue on Neutrino ...
Pietro Antonioli, Richard Tresch Fienberg, Fabrice Fleurot, Yoshiyuki Fukuda, Walter Fulgione, Alec Habig, Jaret Heise, Arthur B McDonald, Corrinne Mills, Toshio Namba, Leif J Robinson, Kate Scholberg, Michael Schwendener, Roger W Sinnott, Blake Stacey, Yoichiro Suzuki, Réda Tafirout, Carlo Vigorito, Brett Viren, Clarence Virtue, Antonino Zichichi   +20 more
openaire   +3 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Early warning systems - empirical evidence

Tržište, 2012
Despite the importance of early warning systems (EWS) in revealing weak signals on environmental changes and in constructing a solid base for timely and appropriate business response, particularly against the backdrop of business crises, empirical ...
Davor Labaš, Alexandra Rausch, Nidžara Osmanagić Bedenik   +2 more
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source