Results 61 to 70 of about 14,110,747 (283)

Malaria epidemic early warning and detection in African highlands. [PDF]

, 2004
Malaria epidemics have long been known to recur in the African highlands. Efforts to develop systems of early warning and detection for epidemics are outlined here with special emphasis on the Highland Malaria Project (HIMAL).
de Vlas, Sake, Cox, J, Ochola, Samuel, Beard, B, Langi, Peter, Cox, Jonathan, Langi, P, Hay, Simon I, Abeku, TA, Beard, Brian, Ochola, S, Hay, SI, Abeku, Tarekegn A, de Vlas, Sake J   +13 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Landslide early warning systems (LEWS)

, 2022
Landslide Early Warning Systems are described in numerous articles, and research works around the world. But what actually is this (and what is it not) and what are the components of it? In order to deal with these questions, first it has to be explained
Arnhardt, Christian
core   +3 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Consideration of cost-efficient early warning system utilizing existing analogue radio broadcasting in Indonesia

MATEC Web of Conferences, 2018
Early warning systems can increase disaster management capacity. Indonesia worked out the national development policy direction of 2015 – 2019 containing establishment of early warning systems.
Kamei Masashi, Gingging Rahadian, Dinga Ariza, Winata Widi   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Early detection of ecosystem regime shifts: A multiple method evaluation for management application [PDF]

, 2012
Critical transitions between alternative stable states have been shown to occur across an array of complex systems. While our ability to identify abrupt regime shifts in natural ecosystems has improved, detection of potential early-warning signals ...
Christian Möllmann (152854), Otto, Saskia, Gardmark, A., Joachim P Gröger, Georgs Kornilovs, Otto, Saskia A., Moellmann, Christian, Dakos, Vasilis, Anna Gårdmark (152842), Otto Saskia A., Groger, J.P., Dakos, V., Dakos Vasilis, Vasilis Dakos, Saskia A. Otto (152850), Groeger, Joachim P, Kornilovs, G., Georgs Kornilovs (152846), Groeger, Joachim P., Kornilovs Georgs, Möllmann Christian, Vasilis Dakos (150752), Lindegren Martin, Lindegren, Martin, Gardmark, Anna, Lindegren, M., Christian Möllmann, Joachim P. Gröger (152838), Gröger Joachim P., Mollmann, C., Martin Lindegren, Kornilovs, Georgs, Saskia A Otto, Gårdmark Anna, Otto, S.A., Martin Lindegren (127611), Gröger, Joachim, Anna Gårdmark, Möllmann, Christian, Gröger, Joachim Paul, Lindegren, Martin,, Groeger, Joachim P,, Otto, Saskia A.,, Swedish University of Agricultural Sciences., Sveriges lantbruksuniversitet., Möllmann, Christian,, Dakos, Vasilis,, Gårdmark, Anna,, Kornilovs, Georgs,   +48 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The seven main challenges of an early warning system architecture

, 2013
In this paper, we describe the work on the system architecture that is being developed in the EU FP7 project TRIDEC on “Collaborative, Complex and Critical Decision-Support in Evolving Crises”.
Mossgraber, Jurgen, Chaves, Fernando, Middleton, Stuart, Zlatev, Z., Tao, Ran   +4 more
core   +1 more source