Results 81 to 90 of about 4,835,504 (248)

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci   +10 more
wiley   +1 more source

Extubation outside the usual chair position: is it possible? Case report

open access: yesJournal of Mechanical Ventilation
Background The withdrawal of ventilatory support is usually carried out in bed; sometimes patients can be extubated outside the usual position as in chair in special cases; benefiting early mobilization which is associated with reducing hospital stay ...
Andrés M Enríquez-Popayán   +1 more
doaj   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Reducing the protein content in diets for weaner pigs to control post-weaning diarrhoea: physiological and metabolic responses of the gastrointestinal tract [PDF]

open access: yes, 2010
A series of experiments was conducted with weaner pigs to examine the effects of dietary protein content, duration of feeding diets after weaning and enterotoxigenic Escherichia coli (ETEC) infection on physiological and metabolic responses of the ...
Heo, Jung-Min
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Effect of weaning strategies on biosynthesis of oxylipids in Holstein dairy calves

open access: yesJDS Communications
The aim of this study was to determine the effect of the weaning calves at 2 ages (early vs. late) and 2 weaning paces (abrupt over 3 d vs. gradual over 14 d) on plasma oxylipids.
A.R. Wolfe   +6 more
doaj   +1 more source

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata   +9 more
wiley   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya   +9 more
wiley   +1 more source

Managemental influences on the selective proliferation of two strains of haemolytic Escherichia coli in weaned pigs [PDF]

open access: yes, 1988
In an experimental study on a piggery it was found that haemolytic Escherichia coli of O-serotypes 138 or 139 proliferated in the intestinal tracts of pigs following weaning, with E.
Fu, Z.F.   +3 more
core  

Growth performance of Girolando and Guzolando calves under contrasting early-life management systems: a retrospective study in a tropical climate dairy farm

open access: yesJournal of Applied Animal Research
This retrospective study evaluated how two early-life management systems influenced calf growth and health in a dairy operation in Coclé, Panamá. The Individual Weaning Management (IWM) system housed calves in large groups (>10 animals) and weaned them ...
Marlyn De La Torre   +12 more
doaj   +1 more source

Early childhood flexibility practices and patterns: report 2014 [PDF]

open access: yes, 2014
The Early childhood flexibility practices and patterns report highlights recommendations and future directions for early childhood education and care (ECEC) services in providing flexible arrangements for families and local communities.
Early Childhood Australia
core  

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