Results 61 to 70 of about 282,573 (230)
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox+3 more
wiley +1 more source
Self-gravity, self-consistency, and self-organization in geodynamics and geochemistry [PDF]
The results of seismology and geochemistry for mantle structure are widely believed to be discordant, the former favoring whole-mantle convection and the latter favoring layered convection with a boundary near 650 km.
Anderson, Don L.
core
The left-handedness was demonstrated by the simulation with a three-level quantum system in an E3+r -dopped ZrF4-BaF2-LaF3-AlF3-NaF (ZBLAFN) optical fiber. And the left-handedness can be regulated by the incoherent pumping field. Our scheme may provide a
Guo, Hong-Wei+2 more
core +1 more source
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri+7 more
wiley +1 more source
The birth of spacetime atoms as the passage of time
The view that the passage of time is physical finds expression in the classical sequential growth models of Rideout and Sorkin in which a discrete spacetime grows by the partially ordered accretion of new spacetime atoms.Comment: Article based on an ...
Dowker, Fay
core +1 more source
Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi+11 more
wiley +1 more source
Mutual Events in the Cold Classical Transneptunian Binary System Sila and Nunam
Hubble Space Telescope observations between 2001 and 2010 resolved the binary components of the Cold Classical transneptunian object (79360) Sila-Nunam (provisionally designated 1997 CS29).
A.J. Verbiscer+66 more
core +1 more source
Reduction method for thermal analysis of complex aerospace structures [PDF]
A reduction method which combines classical Rayleigh-Ritz modal superposition techniques with contemporary finite-element methods is applied to transient nonlinear thermal analysis of aerospace structures.
Shore, C. P.
core +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source