Results 101 to 110 of about 110,705 (315)

Post-wildfire boreal forest vegetation cover change mapping via information fusion for secondary disaster risk assessments

International Journal of Applied Earth Observations and Geoinformation
Post-wildfire vegetation cover damage and loss can escalate the risks of secondary disasters such as flood, landslide, and water contamination, particularly in a major wildfire affected region where human settlements are situated.
Ying Zhang, Julie Lovitt, Maxim Fortin, Haoyu Fang, Sylvain G. Leblanc, Francis Canisius   +5 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Site-specific apparent optimum air temperature for vegetation photosynthesis across the globe

Scientific Data
The apparent optimum air temperature for vegetation photosynthesis (Topt) is a key temperature parameter in terrestrial ecosystem models estimating daily photosynthesis or gross primary production (GPP, g C/m2/day).
Li Pan, Xiangming Xiao, Yuan Yao, Baihong Pan, Chenglong Yin, Cheng Meng, Yuanwei Qin, Chenchen Zhang   +7 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Local primary production hotspot in the coastal waters of Southampton Island, Nunavut, Canada, in summer 2019

Arctic Science
The marine region surrounding Southampton Island, northwestern Hudson Bay, Canada supports relatively large populations of marine mammals and seabirds. However, little information exists about primary production at the base of the marine food web.
Elizabeth H. Kitching, Christine Michel, Lisa C. Matthes, Laura Castro de la Guardia, Zou Zou A. Kuzyk, Audrey Limoges, Jens K. Ehn, Tim N. Papakyriakou, C.J. Mundy   +8 more
doaj   +1 more source

Desert Movement Predictor and Farmabooths: Two Earth Observation Based Applications for Pan-African Development

, 2012
Ricardo Topham, Monica Ebert, Stavros Georgakas, Rafael Hernández, Christopher Johnson, Hemil Modi, Jeffrey Osborne   +6 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Towards enhanced Sargassum monitoring in the Caribbean Sea

Scientific Reports
Monitoring Sargassum along the coasts of the Greater Caribbean has become essential due to recurrent blooms since 2018, which bring severe ecological, economic, and social impacts that accumulate yearly.
Javier Arellano-Verdejo, Hugo E. Lazcano-Hernandez, Jorge Prado Molina, Uriel de Jesús Mendoza Castillo, Víctor Manuel Jiménez Escudero, Francisco Javier Osorno Covarrubias, Gabriela Gómez Rodríguez, José Antonio Quintero Pérez, Steven Czitrom Baus, Iván Penié Rodríguez, Guadalupe Tapia Varela, Ilma Maclovia Huy Domínguez   +11 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

High-resolution geophysical monitoring of moisture accumulation preceding slope movement—a path to improved early warning

Environmental Research Letters
Slope failures are an ongoing global threat leading to significant numbers of fatalities and infrastructure damage. Landslide impact on communities can be reduced using efficient early warning systems to plan mitigation measures and protect elements at ...
Arnaud Watlet, Paul Wilkinson, Jim Whiteley, Adrian White, Sebastian Uhlemann, Russell Swift, Susanne Ouellet, Chris Minto, Philip Meldrum, Lee Jones, David Gunn, Alastair Godfrey, Ben Dashwood, Roger Crickmore, Paul Clarkson, James Boyd, Jonathan Chambers   +16 more
doaj   +1 more source