Results 91 to 100 of about 1,468,027 (343)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Naturally occurring radionuclides and Earth sciences

open access: yesAnnals of Geophysics, 1997
Naturally occurring radionuclides are used in Earth sciences for two fundamental purposes: age determination of rocks and minerals and studies of variation of the isotopic composition of radiogenic nuclides.
G. Ferrara
doaj   +1 more source

STS-9: Orbital Workshop Spacelab to Fly on Ninth Shuttle Mission [PDF]

open access: yes
The first non-astronants are discussed. Spacelab is described. Spacelab objectives, Spacelab 1 investigations, atmospheric physics and Earth observations, space plasma physics, solar physics and astronomy, material sciences and technology development ...

core   +1 more source

Lidar remote sensing from space: NASA's plans in the Earth sciences [PDF]

open access: yes, 1986
A multidisciplinary study of the Earth System to provide a better understanding of the complex interrelated processes involved in the system, the Earth Observing System (EOS), is being developed. Capabilities of the Space Station, both the polar orbiting
Curran, R. J.
core   +1 more source

Neutrino tomography - Learning about the Earth's interior using the propagation of neutrinos

open access: yes, 2006
Because the propagation of neutrinos is affected by the presence of Earth matter, it opens new possibilities to probe the Earth's interior. Different approaches range from techniques based upon the interaction of high energy (above TeV) neutrinos with ...
A. B. Borisov   +36 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Validating the application of cyclic hydraulic pressure pulses to reduce breakdown pressure in granite

open access: yesiScience
Summary: As the geoenergy sector moves toward more sustainable practices, an emerging field of research is the proposed utilization of cyclic hydraulic pressure pulses to safely and efficiently enhance productivity.
Jackie Evan Kendrick   +7 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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