Results 91 to 100 of about 249,122 (281)

On making disability in rural places more visible: challenges and opportunities [Introduction to a special issue] [PDF]

open access: yes, 2017
This essay prefaces a special issue of the Journal of Rural Studies (JRS) concerned with a sub-field of inquiry that might be termed the rural geography of disability, addressing multiple dimensions of disability, physical and mental, associated with ...
Chouinard, Vera   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Book Review

open access: yesLatin American Journal of Sedimentology and Basin Analysis, 2021
The origin of Geomorphology can be referred to 2500 years ago when the ancient Greek, Roman, Arab and Chinese philosophers tried to comprehend the occurrence of earthquakes, volcanoes and the presence of seashells at high mountains elevations.
Diana G. Cuadrado
doaj   +2 more sources

Earth study from space [PDF]

open access: yes
The significance that space studies are making to all Earth sciences in the areas of geography, geodesy, cartography, geology, meteorology, oceanology, agronomy, and ecology is discussed.
Sidorenko, A. V.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

What children want to know about their world. [PDF]

open access: yes, 1952
Thesis (Ed.M.)--Boston ...
Capiferri, Margaret Elizabeth   +10 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Evaluation of the Climate Change Effect on Minimum and Maximum Temperatures and the Reference Evapotranspiration in the Lake Urmia Basin Using CMIP6 Models [PDF]

open access: yesپژوهشنامه مدیریت حوزه آبخیز
Extended Abstract Background: Climate change as an influential phenomenon causes changes in climate systems, increasing both the temperature and the moisture capacity of the atmosphere so that the increase in global temperature has increased the ...
Ameneh Yahyavi Dizaj   +2 more
doaj  

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