Results 131 to 140 of about 1,185,812 (300)
Prescreening-Based Subset Selection for Improving Predictions of Earth System Models With Application to Regional Prediction of Red Tide. [PDF]
Front Earth Sci, 2022 Elshall AS +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
A Machine Learning Framework to Evaluate Vegetation Modeling in Earth System Models
Journal of Advances in Modeling Earth SystemsVegetation gross primary productivity (GPP) is the single largest carbon flux of the terrestrial biosphere which, in turn, is responsible for sequestering 25%–30% of anthropogenic carbon dioxide emissions.
Ranjini Swaminathan +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Earth system models for regional environmental management of red tide: Prospects and limitations of current generation models and next generation development. [PDF]
Environ Earth Sci, 2022 Elshall AS +6 more
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Underestimated Land Heat Uptake Alters the Global Energy Distribution in CMIP6 Climate Models
Geophysical Research LettersCurrent global warming results in an uptake of heat by the Earth system, which is distributed among the different components of the climate system. However, current‐generation climate models deliver heat inventory and partitioning estimates of Earth ...
Norman Julius Steinert +7 more
doaj +1 more source
Quantitative modelling of the human–Earth System a new kind of science?
, 2013 The five grand challenges set out for Earth System Science by the International Council for Science in 2010 require a true fusion of social science, economics and natural science—a fusion that has not yet been achieved.
Brede, Markus +2 more
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