Ebola Hemorrhagic Shock Syndrome-on-a-Chip
Summary: Ebola virus, for which we lack effective countermeasures, causes hemorrhagic fever in humans, with significant case fatality rates. Lack of experimental human models for Ebola hemorrhagic fever is a major obstacle that hinders the development of
Abidemi Junaid +9 more
doaj +1 more source
Context: Ebola hemorrhagic fever (EHF) is amongst severe and fatal viral hemorrhagic fevers. In February 2014, a strain of the Ebola virus appeared in Guinea and then in Liberia, Sierra Leone, and Mali. The aim of this study was to review the literature on EHF and discuss its routes of transmission and prevention.
Maryam Keshtkar Jahromi +1 more
openaire +2 more sources
Emergence of deadly viral haemorrhagic fever disease outbreaks in West Africa
Recent viral hemorrhagic fever (VHF) disease outbreaks caused by Ebola virus (EBOV) and Marburg virus (MARV) in West Africa are unique and alarming.
Widaliz Vega-Rodriguez, Hinh Ly
doaj +1 more source
Sex Differences in Response to Viral Vector Vaccines-Implications for Future Vaccine Design. [PDF]
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Grewe I, Zoran T, Addo MM.
europepmc +2 more sources
Ebolavirosis: a 2014 Review for Clinicians
Ebolavirosis, like Marburgvirosis, are African zoonosis, and for both the primary animal reservoir are bats. It is a typical acute haemorrhagic fever, characterized by a high lethality rate.
Jaime Nina
doaj +1 more source
A review of epidemiological parameters from Ebola outbreaks to inform early public health decision-making. [PDF]
The unprecedented scale of the Ebola outbreak in West Africa has, as of 29 April 2015, resulted in more than 10,884 deaths among 26,277 cases. Prior to the ongoing outbreak, Ebola virus disease (EVD) caused relatively small outbreaks (maximum outbreak ...
Bento, AI +4 more
core +1 more source
Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008 [PDF]
A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
A Grolla +66 more
core +3 more sources
Predicting the extinction of Ebola spreading in Liberia due to mitigation strategies [PDF]
The Ebola virus is spreading throughout West Africa and is causing thousands of deaths. In order to quantify the effectiveness of different strategies for controlling the spread, we develop a mathematical model in which the propagation of the Ebola virus
Aragao Rego, H. H. +3 more
core +5 more sources
Containing the threat - don't forget Ebola [PDF]
In 2000, Uganda experienced the largest outbreak of Ebola fever ever described.
Geisbert, Jonathan Cohen, Lamunu
core +4 more sources
Interventions to Control Virus Transmission During an Outbreak of Ebola Hemorrhagic Fever: Experience from Kikwit, Democratic Republic of the Congo, 1995. [PDF]
On 6 May 1995, the Médecins sans Frontières (MSF) coordinator in Kinshasa, Democratic Republic of the Congo (DRC), received a request for assistance for what was believed to be a concurrent outbreak of bacillary dysentery and viral hemorrhagic fever ...
Kerstiëns, B, Matthys, F
core +2 more sources

