Results 41 to 50 of about 298,452 (154)

Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time

Nature Communications, 2020
Outbreaks of viral hemorrhagic fevers highlight the need for sensitive, field-deployable diagnostics. Here the authors present a CRISPR-based SHERLOCK platform with field protocol and mobile app for Ebola and Lassa fever outbreaks.
Kayla G. Barnes, Anna E. Lachenauer, Adam Nitido, Sameed Siddiqui, Robin Gross, Brett Beitzel, Katherine J. Siddle, Catherine A. Freije, Bonnie Dighero-Kemp, Samar B. Mehta, Amber Carter, Jessica Uwanibe, Fehintola Ajogbasile, Testimony Olumade, Ikponmwosa Odia, John Demby Sandi, Mambu Momoh, Hayden C. Metsky, Chloe K. Boehm, Aaron E. Lin, Molly Kemball, Daniel J. Park, Luis Branco, Matt Boisen, Brian Sullivan, Mihret F. Amare, Abdulwasiu B. Tiamiyu, Zahra F. Parker, Michael Iroezindu, Donald S. Grant, Kayvon Modjarrad, Cameron Myhrvold, Robert F. Garry, Gustavo Palacios, Lisa E. Hensley, Stephen F. Schaffner, Christian T. Happi, Andres Colubri, Pardis C. Sabeti   +38 more
doaj   +1 more source

Imported viral haemorrhagic fever with a potential for person-to-person transmission: review and recommendations for initial management of a suspected case in Belgium.

, 2002
Viral haemorrhagic fevers are caused by a wide range of viruses. There are 4 types of viruses well known to spread from person to person and able to cause nosocomial outbreaks with a high case fatality rate: an arenavirus (Lassa fever and more ...
Borchert, M., Moreau, M, Borchert, M, Colebunders, R, Moreau, M., Van Esbroeck, M., Van Esbroeck, M, Colebunders, R.   +7 more
core   +1 more source

Ebola Virus Hemorrhagic Fever [PDF]

Microscopy and Microanalysis, 2015
This past year has seen the largest Ebola virus outbreak on record, centered in West Africa in Guinea, Liberia, and Sierra Leone. 1 Cases were first reported in Guinea on March 21, 2014; by March 30, cases were reported in Liberia and in May Sierra Leone also reported cases.
openaire   +1 more source

Use of protective gear and the occurrence of occupational Marburg hemorrhagic fever in health workers from Watsa health zone, Democratic Republic of the Congo.

, 2007
BACKGROUND: Occupational transmission to health workers (HWs) has been a typical feature of Marburg hemorrhagic fever (MHF) outbreaks. The goal of this study was to identify cases of occupational MHF in HWs from Durba and Watsa, Democratic Republic of ...
Libande, Modeste L, MULANGU, S, TSHOMBA, A, Pierre Lefèvre, Muyembe-Tamfum, J. J., Van der Stuyft, Patrick, LIBANDE, ML, Muyembe-Tamfum, Jean-Jacques, Kulidri, Amayo, Tshomba, Antoine, MUYEMBE-TAMFUM, JJ, BORCHERT, M, Antoine Tshomba, Borchert, M., Tshomba, A., Van der Stuyft, P., Libande, M. L., Jean‐Jacques Muyembe‐Tamfum, Modeste L. Libande, Kulidri, A., Amayo Kulidri, Matthias Borchert, Mulangu, Sabue, Mulangu, S., LEFEVRE, P, Sabue Mulangu, KULIDRI, A, Patrick Van der Stuyft, Borchert, Matthias, Lefevre, Pierre, Lefèvre, P.   +30 more
core   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, Volume 3, Issue 3, September 2026.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

A THEORETICAL STUDY ON FRACTIONAL EBOLA HEMORRHAGIC FEVER MODEL

Fractals, 2021
The Ebola virus infection (EVI), generally known as Ebola hemorrhagic fever, is a major health concern. The occasional outbreaks of virus occur primarily in certain parts of Africa. Many researches have been devoted to the study of the Ebola virus disease.
Momani, Shaher, Chauhan, R. P., Kumar, Sunil, Hadid, Samir   +3 more
openaire   +2 more sources

Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

Emerging Infectious Diseases, 2014
Sierra Leone in West Africa is in a Lassa fever–hyperendemic region that also includes Guinea and Liberia. Each year, suspected Lassa fever cases result in submission of ≈500–700 samples to the Kenema Government Hospital Lassa Diagnostic Laboratory in ...
Randal J. Schoepp, Cynthia A. Rossi, Sheik H. Khan, Augustine Goba, Joseph N. Fair   +4 more
doaj   +1 more source

Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus

Антибиотики и Химиотерапия, 2020
The article presents an analysis of research evaluating the effectiveness of nonspecific means of emergency prevention and treatment of Ebola virus disease.
T. E. Sizikova, v. N. Lebedev, A. A. Petrov, S. V. Borisevich   +3 more
doaj   +1 more source

Systemic and Mucosal Immune Responses From Serotype‐Switched Viral‐Vectored Ebola Vaccines

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Ebola virus is a highly virulent pathogen causing severe hemorrhagic fever with 25%–90% mortality. The 2014 outbreak infected over 28,000 people, causing 11,325 deaths. Although there is one FDA‐approved vaccine available for limited use, additional vaccines are needed.
Joshua Wiggins, Adthakorn Madapong, Eric Weaver   +2 more
wiley   +1 more source

Qualitative Assessment of One Health Operationalization at the Central Level and in Two Border Districts of Sierra Leone

Public Health Challenges, Volume 5, Issue 3, September 2026.
Implementation of the One Health approach in Sierra Leone was stronger at the central level than in districts and communities, where coordination, surveillance, workforce capacity, and funding were limited. Strengthening integrated systems and dedicated financing is essential for effective prevention and control of zoonotic disease threats.
Joseph Anderson Bunting‐Graden, Fatmata Sawaneh, Alhassan Mayei, Monya Konneh, Patrick Fatoma, Emmanuel Komba Finoh, Lily Kainwo, Wesen Konteh, Mukeh Kenneth Fahnbulleh, Klaere Heyden, Mohamed Alex Vandi, Foday Sahr, Adel Hussein Elduma Abdalla, Rashid Ansumana, Kinley Wangdi, Philip P. Mshelbwala   +15 more
wiley   +1 more source