Results 51 to 60 of about 17,340 (209)

Reemerging Sudan Ebola Virus Disease in Uganda, 2011

Emerging Infectious Diseases, 2012
Two large outbreaks of Ebola hemorrhagic fever occurred in Uganda in 2000 and 2007. In May 2011, we identified a single case of Sudan Ebola virus disease in Luwero District.
Trevor Shoemaker, Adam MacNeil, Stephen Balinandi, Shelley Campbell, Joseph Francis Wamala, Laura K. McMullan, Robert Downing, Julius Lutwama, Edward Mbidde, Ute Ströher, Pierre E. Rollin, Stuart T. Nichol   +11 more
doaj   +1 more source

Elevated l-threonine is a biomarker for Lassa fever and Ebola

Virology Journal, 2020
Background Lassa fever and Ebola are characterized by non-specific initial presentations that can progress to severe multisystem illnesses with high fatality rates.
Trevor V. Gale, John S. Schieffelin, Luis M. Branco, Robert F. Garry, Donald S. Grant   +4 more
doaj   +1 more source

EBOV-RNA test with RT-PCR in ocular fluids of Ebola survivors can help to safely perform cataract surgery [PDF]

, 2018
Since the Ebola virus (EBOV) was discovered in 1976, the recent 2014−2016 Ebola virus disease (EVD) outbreak in West Africa was the largest with 28,600 cases and about 11,300 deaths.
Iozzo, Nicola, Spadea, Leopoldo
core   +1 more source

Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time

Nature Communications, 2020
Outbreaks of viral hemorrhagic fevers highlight the need for sensitive, field-deployable diagnostics. Here the authors present a CRISPR-based SHERLOCK platform with field protocol and mobile app for Ebola and Lassa fever outbreaks.
Kayla G. Barnes, Anna E. Lachenauer, Adam Nitido, Sameed Siddiqui, Robin Gross, Brett Beitzel, Katherine J. Siddle, Catherine A. Freije, Bonnie Dighero-Kemp, Samar B. Mehta, Amber Carter, Jessica Uwanibe, Fehintola Ajogbasile, Testimony Olumade, Ikponmwosa Odia, John Demby Sandi, Mambu Momoh, Hayden C. Metsky, Chloe K. Boehm, Aaron E. Lin, Molly Kemball, Daniel J. Park, Luis Branco, Matt Boisen, Brian Sullivan, Mihret F. Amare, Abdulwasiu B. Tiamiyu, Zahra F. Parker, Michael Iroezindu, Donald S. Grant, Kayvon Modjarrad, Cameron Myhrvold, Robert F. Garry, Gustavo Palacios, Lisa E. Hensley, Stephen F. Schaffner, Christian T. Happi, Andres Colubri, Pardis C. Sabeti   +38 more
doaj   +1 more source

Molecular identification of adenoviruses associated with respiratory infection in Egypt from 2003 to 2010. [PDF]

, 2014
BACKGROUND: Human adenoviruses of species B, C, and E (HAdV-B, -C, -E) are frequent causative agents of acute respiratory infections worldwide. As part of a surveillance program aimed at identifying the etiology of influenza-like illness (ILI) in Egypt ...
A Kandeel, AC Kroes, Adriana Kajon, AE Kajon, AE Kajon, AH Kamel, AK Adhikary, Amany Elgohary Sheta, Amel Mohamed Nageib Hasanin, Anne M Gaynor, B Biere, B Cao, B Chmielewicz, B Lin, BDJ Hess, CD Brandt, Claire Cornelius, CT Garnett, D Metzgar, D Metzgar, G Wadell, GC Gray, GJ Vora, H Schmitz, HA El-Mahallawy, HG Pereira, HS Houng, I Luksic, J Abd-Jamil, JP Fox, JY Hong, Katherine C Horton, KL Russell, LK Crawford-Miksza, M El Sayed Zaki, M El-Sayed Zaki, MA Ryan, MKA Deming, OA Adeyemi, OA Adeyi, Pola N Demian, R Al-Toum, Rania Siam, RJ Cooper, S Alharbi, S Levin, SK Schepetiuk, SY Ou, T Kojaoghlanian, TE-MB El-Shewy, TT Pham, W Saitoh-Inagawa, W Xu, W Xu, WA Andiman, WC Russell, Y Chu, YJ Kim   +57 more
core   +1 more source

Recommendations for dealing with waste contaminated with Ebola virus: a Hazard Analysis of Critical Control Points approach [PDF]

, 2016
Objective To assess, within communities experiencing Ebola virus outbreaks, the risks associated with the disposal of human waste and to generate recommendations for mitigating such risks.
Ahmed A Mohamedani, Benedict M Mutua, Brainard, Chepurnov, Diana J Bell, Edward Muchiri, Guy Howard, Harvey Minnigh, Iain Lake, Joseph Matofari, Julii Brainard, Julius M Ndambuki, Katherine Pond, Kelly L Edmunds, Lutendo S Mudau, Maggie Montgomery, Mark D Sobsey, Mark Zeitoun, Mike van der Es, Paul R Hunter, Peter Maes, Roger Few, Samir Dervisevic, Samira Abd Elrahman, Sarah Morter, Tsimbiri P Fedha   +25 more
core   +2 more sources

Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus

Антибиотики и Химиотерапия, 2020
The article presents an analysis of research evaluating the effectiveness of nonspecific means of emergency prevention and treatment of Ebola virus disease.
T. E. Sizikova, v. N. Lebedev, A. A. Petrov, S. V. Borisevich   +3 more
doaj   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

Emerging Infectious Diseases, 2014
Sierra Leone in West Africa is in a Lassa fever–hyperendemic region that also includes Guinea and Liberia. Each year, suspected Lassa fever cases result in submission of ≈500–700 samples to the Kenema Government Hospital Lassa Diagnostic Laboratory in ...
Randal J. Schoepp, Cynthia A. Rossi, Sheik H. Khan, Augustine Goba, Joseph N. Fair   +4 more
doaj   +1 more source

Plant phenology supports the multi-emergence hypothesis for ebola spillover events [PDF]

, 2017
Ebola virus disease outbreaks in animals (including humans and great apes) start with sporadic host switches from unknown reservoir species. The factors leading to such spillover events are little explored.
Douglas, Noah E., Isokpehi, Raphael D., Johnson, Brianna, McGill, Ayana, Sivasundaram, Seenith, Wollenberg Valero, Katharina C., Wootson, Kiara   +6 more
core   +1 more source