Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1650-1661, June 2026.AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland +48 more
wiley +1 more source
Projections of epidemic transmission and estimation of vaccination impact during an ongoing Ebola virus disease outbreak in Northeastern Democratic Republic of Congo, as of Feb. 25, 2019. [PDF]
, 2019 BackgroundAs of February 25, 2019, 875 cases of Ebola virus disease (EVD) were reported in North Kivu and Ituri Provinces, Democratic Republic of Congo.
Hoff, Nicole A +12 more
core +1 more source
Infectious Disease Response in Tanzania: Enhanced Strategies From the 2023 to 2025 Marburg Outbreaks
Public Health Challenges, Volume 5, Issue 2, June 2026.ABSTRACT The 2023 Marburg virus disease (MVD) outbreak in Tanzania, which resulted in nine confirmed cases and six deaths (case fatality rate [CFR]: 66.7%), served as a critical stress test of the national health system, revealing significant gaps in outbreak preparedness across surveillance, laboratory capacity, and infection prevention and control ...
Huda Haque +6 more
wiley +1 more source
Isolation and Phylogenetic Characterization of Ebola Viruses Causing Different Outbreaks in Gabon
Emerging Infectious Diseases, 1997 Three outbreaks of Ebola hemorrhagic fever have recently occurred in Gabon. Virus has been isolated from clinical materials from all three outbreaks, and nucleotide sequence analysis of the glycoprotein gene of the isolates and virus present in clinical ...
Marie-Claude Georges-Courbot +15 more
doaj +1 more source
Presence and persistence of Ebola or Marburg virus in patients and survivors: A rapid systematic review [PDF]
, 2016 Background: The 2013-15 Ebola outbreak was unprecedented due to sustainedtransmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance ...
Brainard, Julii +4 more
core +3 more sources
Community-based Crisis Response: Evidence from Sierra Leone’s Ebola Outbreak [PDF]
, 2020 Postmortems on the recent Ebola outbreak in West Africa suggest that effective community engagement helped slow transmission by encouraging people to come forward and be tested.
Christensen, Darin +4 more
core +1 more source
Ebola Hemorrhagic Fever: Case Fatality Rate 90%? [PDF]
Central European Journal of Public Health, 2014 Revisión
openaire +3 more sources
Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.ABSTRACT Background Since December 2019, SARS‐CoV‐2 has infected over 700 million people and caused > 7 million deaths. While much of the global north was severely affected, sub‐Saharan Africa was relatively spared. Possible reasons include a younger population, fewer comorbidities, and pre‐existing immunity.
Robert J. Samuels +11 more
wiley +1 more source
Molecular detection of dengue virus in patients suspected of Ebola virus disease in Ghana.
PLoS ONE, 2018 Dengue fever is known to be one of the most common arthropod-borne viral infectious diseases of public health importance. The disease is now endemic in more than 100 countries in Africa, the Americas, the Eastern Mediterranean, Southeast Asia and the ...
Joseph Humphrey Kofi Bonney +10 more
doaj +1 more source
A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova +5 more
doaj +1 more source