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Ebola: Lessons on Vaccine Development
Annual Review of Microbiology, 2018The West African Ebola virus (EBOV) epidemic has fast-tracked countermeasures for this rare, emerging zoonotic pathogen. Until 2013–2014, most EBOV vaccine candidates were stalled between the preclinical and clinical milestones on the path to licensure, because of funding problems, lack of interest from pharmaceutical companies, and competing ...
Heinz, Feldmann +2 more
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Current Ebola Virus Vaccine Progress
BioDrugs, 2019Over 40 years since the discovery of Ebola virus, the anti-Ebola virus vaccine efforts of the past 2 decades have culminated in over 12 different vaccine candidates that have been placed into a number of clinical trial phases, past and present. Of these 12 vaccines, four candidates are up to or in phase II clinical trials, and only one has completed ...
Andrea, Marzi, Chad E, Mire
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Nature, 2000
The first vaccine to protect primates from Ebola virus offers hope for a human version, Valerie Depraetere reports. .
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The first vaccine to protect primates from Ebola virus offers hope for a human version, Valerie Depraetere reports. .
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Legal preparedness and Ebola vaccines
The Lancet, 2015On Dec 9, 2014, US Secretary of Health and Human Services Sylvia Burwell issued a declaration under the US Public Readiness and Emergency Preparedness Act to provide immunity from legal claims in the USA related to manufacturing, testing, development, distribution, and administration of three candidate Ebola vaccines except in instances of willful ...
Halabi, Sam F., Monahan, John T
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Ebola: evaluating vaccines during epidemics
BMJ, 2015Innovative, flexible, and validated study designs need to be ready for next time Will vaccines be effective? Would trials be ethical? Are trials even required? These are some of the questions that dominated health policy discourse throughout the current Ebola tragedy in West Africa.
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Vaccinate children despite Ebola
Science, 2015Epidemiology![Figure][1] Tanzanian mothers awaiting vaccinations IMAGE: STEVE RINGMAN/MCT/NEWSCOM During the medical emergency caused by the Ebola virus outbreak in West Africa, routine childhood vaccination programs have been suspended.
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Science, 2014
NewLink Genetics says it might have enough doses ready by spring to vaccinate most people at risk.
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NewLink Genetics says it might have enough doses ready by spring to vaccinate most people at risk.
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