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The Evolution of Medical Countermeasures for Ebola Virus Disease: Lessons Learned and Next Steps
Vaccines, 2022 The Ebola virus disease outbreak that occurred in Western Africa from 2013–2016, and subsequent smaller but increasingly frequent outbreaks of Ebola virus disease in recent years, spurred an unprecedented effort to develop and deploy effective vaccines ...
Ian Crozier +10 more
doaj +1 more source
Identification of Novel Adjuvants for Ebola Virus-Like Particle Vaccine
Vaccines, 2020 Ebola virus disease is a severe disease, often fatal, with a mortality rate of up to 90%. Presently, effective treatment and safe prevention options for Ebola virus disease are not available. Therefore, there is an urgent need to develop control measures
Huapeng Feng +7 more
doaj +1 more source
Ebola vaccination – Authors' reply [PDF]
The Lancet, 2015 2016-03-19T19:12 ...
Department of Biostatistics, University of Florida, Gainesville, FL, USA ( host institution ) +5 more
openaire +3 more sources
Vaccines against Ebola virus [PDF]
Vaccine, 2018 We have just witnessed the largest and most devastating outbreak of Ebola virus disease, which highlighted the urgent need for development of an efficacious vaccine that could be used to curtail future outbreaks. Prior to 2014, there had been limited impetus worldwide to develop a vaccine since the virus was first discovered in 1976.
Venkatraman, N +3 more
openaire +3 more sources
Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]
, 2008 The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher +105 more
core +2 more sources
Development of a TB vaccine trial site in Africa and lessons from the Ebola experience
BMC Public Health, 2020 Tuberculosis is the deadliest infection of our time. In contrast, about 11,000 people died of Ebola between 2014 and 2016. Despite this manifest difference in mortality, there is now a vaccine licensed in the United States and by the European Medicines ...
G. Kaguthi +13 more
doaj +1 more source
Projections of Ebola outbreak size and duration with and without vaccine use in Équateur, Democratic Republic of Congo, as of May 27, 2018. [PDF]
, 2018 As of May 27, 2018, 6 suspected, 13 probable and 35 confirmed cases of Ebola virus disease (EVD) had been reported in Équateur Province, Democratic Republic of Congo. We used reported case counts and time series from prior outbreaks to estimate the total
Ackley, Sarah +17 more
core +2 more sources
Cell Reports, 2018 Summary: Comparative immune response profiling is important for selecting next-generation vaccines. We comprehensively evaluated the antibody responses from a panel of nine respiratory vaccines against Ebola virus (EBOV) derived from human and avian ...
Michelle Meyer +7 more
doaj +1 more source