Results 51 to 60 of about 41,454 (219)

Immune-Complex Mimics as a Molecular Platform for Adjuvant-Free Vaccine Delivery [PDF]

open access: yes, 2013
Protein-based vaccine development faces the difficult challenge of finding robust yet non-toxic adjuvants suitable for humans. Here, using a molecular engineering approach, we have developed a molecular platform for generating self-adjuvanting immunogens
A Demissie   +68 more
core   +2 more sources

Strengthening vaccines and medicines manufacturing capabilities in Africa: challenges and perspectives

open access: yesEMBO Molecular Medicine, 2022
Africa carries a high burden of infectious diseases. Every year, millions of Africans contract tuberculosis, malaria, and many other diseases. Malaria kills hundreds of thousands of children under the age of five years annually.
AbdulRahman A Saied   +4 more
doaj   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

open access: yesInterdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu   +6 more
wiley   +1 more source

Plastics and labor: The case of disposable medical plastics

open access: yesMedical Anthropology Quarterly, EarlyView.
Abstract Plastics are ubiquitous in the contemporary practice of medicine, where they are tied to notions of hygiene and quality of care. However, when plastics first infiltrated global medical practice, they did so because of considerations related to patient comfort and durability.
Gauri Pathak
wiley   +1 more source

Zika, Pregnancy, and the Law [PDF]

open access: yes, 2017
The public health emergency surrounding the spread of the Zika virus has resurrected and brought into sharp relief some of the most vexing questions surrounding the relationship between pregnancy and law: the appropriate circumstances, if any, in which ...
Halabi, Sam F.
core   +3 more sources

Fighting Novel Diseases amidst Humanitarian Crises [PDF]

open access: yes, 2019
Humanitarian crises are becoming more prevalent and, frequently, more complex, in zones of mis-governance, lack of government presence, and even active conflict, marked by public mistrust and insecurity. The WHO and other health emergency responders lack
Friedman, Eric A.   +2 more
core   +2 more sources

A comparative computational genomics of Ebola Virus Disease strains: In-silico Insight for Ebola control

open access: yesInformatics in Medicine Unlocked, 2018
Ebola Virus Disease (EVD), is a national epidemic in Countries affected. It is also a potential global public health pandemic. The menace of the disease outbreak among West and Central African nations, in recent years, has resulted in the death of many ...
Olugbenga Oluwagbemi, Olaitan Awe
doaj   +1 more source

Chimpanzee Adenovirus Vector Ebola Vaccine

open access: yesNew England Journal of Medicine, 2017
The unprecedented 2014 epidemic of Ebola virus disease (EVD) prompted an international response to accelerate the availability of a preventive vaccine. A replication-defective recombinant chimpanzee adenovirus type 3-vectored ebolavirus vaccine (cAd3-EBO), encoding the glycoprotein from Zaire and Sudan species, that offers protection in the nonhuman ...
Julie E, Ledgerwood   +26 more
openaire   +2 more sources

Law’s power to safeguard global health: a Lancet–O’Neill Institute, Georgetown University Commission on Global Health and the Law [PDF]

open access: yes, 2015
The law-–global, national, and subnational–-plays a vital, yet often underappreciated, role in safeguarding and promoting the public’s health. In this article, we launch the Lancet-O’Neill Institute, Georgetown University Commission on Global Health and ...
DeBartolo, Mary C.   +3 more
core   +3 more sources

Ebolavirus Evolution: Past and Present. [PDF]

open access: yesPLoS Pathogens, 2015
The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV) has now been around for almost 50 years. In this review, we discuss past and present outbreaks of
Marc-Antoine de La Vega   +2 more
doaj   +1 more source

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