Results 141 to 150 of about 1,772,484 (313)

Repurposed therapeutic agents targeting the Ebola virus: a protocol for a systematic review [PDF]

, 2015
BACKGROUND: The recent Ebola epidemic in western Africa developed into an acute public health emergency of unprecedented level in modern times. The treatment provided in most cases has been limited to supportive care, as no approved therapies are ...
Hussein Sweiti, Obinna Ekwunife, Stefan K. Lhachimi, Thomas Jaschinski   +3 more
core   +3 more sources

A cellular model of TDP‐43 induces phosphorylated TDP‐43 aggregation with distinct changes in solubility and autophagy dysregulation

The FEBS Journal, EarlyView.
TDP‐43 protein plays a pathological role in sporadic and familial amyotrophic lateral sclerosis (ALS). Here, we developed a cellular model overexpressing TDP‐43 with three mutations linked to familial ALS, termed ‘3X‐TDP‐43’. Mutant 3X‐TDP‐43 expression showed deficits in autophagy flux and colocalization with stress granules.
Matthew B. Dopler, Muhammad I. Abeer, Sanaz Arezoumandan, Keyshawn Cox, Tyler L. Petersen, Esther H. Daniel, Carlton L. Cannon III, Angelica Bautista, Kennedy D. Blancher, Alysia M. Bland, Kylie J. Bond, Dominque A. Davis, Jessica M. Francois, Eliana J. McCray, Justin M. Morgan, Jessica L. Pulliam, Zymir A. Robinson, Mykia J. Taylor, James A. Dowell, Nigel J. Cairns, Michael A. Gitcho   +20 more
wiley   +1 more source

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

PLoS Medicine, 2018
Background Despite repeated outbreaks, in particular the devastating 2014–2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD).
J. Guedj, G. Piorkowski, Frédéric Jacquot, V. Madelain, Thi Huyen Tram Nguyen, A. Rodallec, S. Gunther, C. Carbonnelle, F. Mentré, H. Raoul, X. D. de Lamballerie   +10 more
semanticscholar   +1 more source

Uveitis and Systemic Inflammatory Markers in Convalescent Phase of Ebola Virus Disease

Emerging Infectious Diseases, 2016
We report a case of probable Zaire Ebola virus–related ophthalmologic complications in a physician from the United States who contracted Ebola virus disease in Liberia.
John R. Chancellor, Sriranjani P. Padmanabhan, Thomas C. Greenough, Richard Sacra, Richard T. Ellison, Lawrence C. Madoff, Rebecca J. Droms, David M. Hinkle, George K. Asdourian, Robert W. Finberg, Ute Stroher, Timothy M. Uyeki, Olga M. Cerón   +12 more
doaj   +1 more source

Exploring the Impact of COVID‐19 on Acute Care Nurses: An Integrative Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To analyse, critique, and synthesise available research to create a unique framework of the impacts of COVID‐19 on acute care nurses. Methods Whittemore and Knafl's framework was used to organise this review. The Mixed Methods Appraisal Tool was used for quality analysis.
Janelle Schentag, Kelly Penz, Helen Vandenberg   +2 more
wiley   +1 more source

Ebola Virüsü

Arşiv Kaynak Tarama Dergisi, 2015
Bu hastalık ismini1976'dailk kezgörüldüğü Kongo Demokratik Cumhuriyetindeki bir köye yakın olarak konumlanmış Ebola Nehrinden alır. Bu hastalığa Filoviridae ailesine mensup bir virüsten sebep olmaktadır. Ebola salgını başladığı günden bu yana temelde Batı Afrika'da yerleşim gösteren dört ülkeyi; Gine, Liberya, Sierra Leone ve Nijerya'yı ...
LAKSHMAN, Anusha, GOYA, Vikas, SHENOY, Hosmar   +2 more
openaire   +3 more sources

Public Health in the Age of Ebola in West Africa [PDF]

, 2014
The Ebola epidemic, with its fast-growing toll and real potential for spreading into much of Africa, including major cities, has the makings of a “Black Swan” event.
Gostin, Lawrence O., Moore, Kristine A., Osterholm, Michael T.   +2 more
core   +2 more sources

A community-engaged infection prevention and control approach to Ebola. [PDF]

, 2015
The real missing link in Ebola control efforts to date may lie in the failure to apply core principles of health promotion: the early, active and sustained engagement of affected communities, their trusted leaders, networks and lay knowledge, to help ...
Banya, Sama S, Corburn, Jason, Gibson, Nancy, Marais, Frederick, Mehtar, Shaheen, Minkler, Meredith, Mwau, Baraka, Ogunsola, Folasade   +7 more
core   +2 more sources

Irregular and Infectious? COVID‐19, Ebola and the Securitization of Migration to Southern Europe

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Securitization scholarship concentrates on the discursive association between undocumented migration, terrorism and crime. Our textual and visual analysis of Italian, Spanish and Maltese newspapers between 2013 and 2020 demonstrates that the discourses securitizing irregular mobility as a health risk became more salient than those linking ...
Eugenio Cusumano, Martina Abisso, Diego Caballero‐Vélez   +2 more
wiley   +1 more source

Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks

Nature, 2021
A. Keita, F. R. Koundouno, Martin Faye, A. Düx, J. Hinzmann, Haby Diallo, A. Ayouba, Frédéric Le Marcis, B. Soropogui, Kékoura Ifono, M. Diagne, M. S. Sow, J. A. Boré, S. Calvignac‐Spencer, N. Vidal, Jacob Camara, M. B. Keita, A. Renevey, A. Diallo, A. Soumah, Saa L Millimono, A. Marí-Saéz, M. Diop, A. Doré, Fodé Y Soumah, Kaka Kourouma, N. J. Vielle, C. Loucoubar, I. Camara, Karifa Kourouma, Giuditta Annibaldis, Assaïtou Bah, A. Thielebein, Meike Pahlmann, S. Pullan, M. Carroll, J. Quick, P. Formenty, Anaïs Legand, Karla Pietro, M. Wiley, N. Tordo, C. Peyrefitte, J. McCrone, A. Rambaut, Y. Sidibé, M. D. Barry, M. Kourouma, Cé D Saouromou, M. Condé, M. Baldé, M. Povogui, S. Keita, Mandiou Diakité, M. Bah, A. Sidibé, Dembo Diakite, F. Sako, F. Traoré, G. Ki-zerbo, P. Lemey, S. Günther, L. Kafetzopoulou, A. Sall, E. Delaporte, S. Duraffour, O. Faye, F. Leendertz, M. Peeters, A. Touré, N. Magassouba   +70 more
semanticscholar   +1 more source