Results 11 to 20 of about 1,946,344 (262)

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

Lancet, The, 2017
Summary Background rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-based candidate vaccine expressing a surface glycoprotein of Zaire Ebolavirus.
A. Henao-Restrepo, A. Camacho, M. Egger, M. W. Carroll, I. Diatta, M. Doumbia, B. Draguez, G. Enwere, R. Grais, S. Gunther, Stefanie Hossmann, S. Watle, M. K. Konde, Eewa Kuisma, Thomas Mauget, G. Norheim, Ximena Riveros, A. Soumah, S. Trelle, Andrea S Vicari, J. Røttingen, M. Kieny   +21 more
semanticscholar   +3 more sources

Viral genomics in Ebola virus research

Nature Reviews Microbiology, 2020
Filoviruses such as Ebola virus continue to pose a substantial health risk to humans. Advances in the sequencing and functional characterization of both pathogen and host genomes have provided a wealth of knowledge to clinicians, epidemiologists and ...
Nicholas Di Paola, M. Sanchez-Lockhart, Xiankun Zeng, J. Kuhn, G. Palacios   +4 more
semanticscholar   +3 more sources

Therapeutic strategies to target the Ebola virus life cycle

Nature Reviews Microbiology, 2019
T. Hoenen, A. Groseth, H. Feldmann
semanticscholar   +3 more sources

Current state of Ebola virus vaccines: A snapshot

PLoS Pathogens, 2021
Why are Ebola virus vaccines needed? Four species of the genus Ebolavirus cause severe and often lethal disease in humans: Sudan ebolavirus (SUDV), Bundibugyo ebolavirus (BDBV), Taï Forest ebolavirus (TAFV), and Zaire ebolavirus (EBOV) [1]. Historically,
Courtney Woolsey, T. Geisbert
semanticscholar   +1 more source

Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

Trials, 2021
Introduction The Ebola virus disease (EVD) outbreak in 2014–2016 in West Africa was the largest on record and provided an opportunity for large clinical trials and accelerated efforts to develop an effective and safe preventative vaccine.
Moses Badio, Edouard Lhomme, Mark Kieh, Abdoul Habib Beavogui, Stephen B. Kennedy, Seydou Doumbia, Bailah Leigh, Samba O. Sow, Alpha Diallo, Daniela Fusco, Matthew Kirchoff, Monique Termote, Renaud Vatrinet, Deborah Wentworth, Helène Esperou, H. Clifford Lane, Jerome Pierson, Deborah Watson-Jones, Céline Roy, Eric D’Ortenzio, Brian Greenwood, Genevieve Chêne, Laura Richert, James D. Neaton, Yazdan Yazdanpanah, the PREVAC study team   +25 more
doaj   +1 more source

Structure of the Ebola virus polymerase complex

Nature, 2022
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although two therapeutic monoclonal antibodies have been approved to treat the Ebola virus disease 1 , 2 , there are no approved broadly reactive drugs to control diverse
Bin Yuan, Qi Peng, Jinlong Cheng, Min Wang, Jin Zhong, Jianxun Qi, G. Gao, Yi Shi   +7 more
semanticscholar   +1 more source

What did we learn from preparing for cross-border transmission of Ebola virus disease into a complex humanitarian setting – The Republic of South Sudan?

Infectious Diseases of Poverty, 2020
Background Following the West Africa Ebola virus disease (EVD) outbreak (2013–2016), WHO developed a preparedness checklist for its member states. This checklist is currently being applied for the first time on a large and systematic scale to prepare for
Olushayo Oluseun Olu, Richard Lako, Joseph Francis Wamala, Patrick Otim Ramadan, Caroline Ryan, Ifeanyi Udenweze, Kibebu Berta, Argata Guracha Guyo, Alex Sokemawu, Michael Tukuru, Henry John Gray, Alex Chimbaru   +11 more
doaj   +1 more source

Predicting the extinction of Ebola spreading in Liberia due to mitigation strategies [PDF]

, 2015
The Ebola virus is spreading throughout West Africa and is causing thousands of deaths. In order to quantify the effectiveness of different strategies for controlling the spread, we develop a mathematical model in which the propagation of the Ebola virus
Braunstein, L. A., Rêgo, H. H. A., Stanley, H. E., Valdez, L. D.   +3 more
core   +5 more sources

Care and COVID 19: Lessons for liberals and neoliberals

Child &Family Social Work, EarlyView., 2023
Abstract Within the liberal political traditions, care is regarded as a private matter, a problem of ethics rather than justice. Social justice is framed as an issue of economics (re/distribution), culture (recognition) and/or politics (representation).
Kathleen Lynch
wiley   +1 more source

Adult and paediatric haematology and clinical chemistry laboratory reference limits for Liberia

African Journal of Laboratory Medicine, 2020
Background: As more research is conducted in Liberia, there is a need for laboratory reference limits for common chemistry and haematology values based on a healthy population. Reference limits from the United States may not be applicable.
Mark W. Kieh, Sarah M. Browne, Greg A. Grandits, Julie Blie, Jestina W. Doe-Anderson, Marie L. Hoover, Bionca Davis, Cavan S. Reilly, James D. Neaton, H. Clifford Lane, Stephen B. Kennedy   +10 more
doaj   +1 more source