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Lancet. Infectious Diseases (Print)BACKGROUND The recombinant vesicular stomatitis virus-Zaire Ebola virus (rVSV-ZEBOV) vaccine is the only WHO prequalified vaccine recommended for use to respond to outbreaks of Ebola virus (species Zaire ebolavirus) by WHO's Strategic Advisory Group of ...
Sophie Meakin +11 more
semanticscholar +1 more source
Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Remdesivir is a nucleotide analog prodrug that has been evaluated in humans against acute Ebola virus disease; it also recently received emergency use authorization for treating COVID-19.
Michael K. Lo +17 more
semanticscholar +1 more source
Viruses, 2020 Filoviruses, such as Ebola virus and Marburg virus, are of significant human health concern. From 2013 to 2016, Ebola virus caused 11,323 fatalities in Western Africa.
Ryan P. Bennett +10 more
doaj +1 more source
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Science, 2014 Evolution of Ebola virus over time The high rate of mortality in the current Ebola epidemic has made it difficult for researchers to collect samples of the virus and study its evolution. Gire et al.
Stephen Gire +57 more
semanticscholar +1 more source
Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008 [PDF]
, 2012 A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
A Grolla +66 more
core +3 more sources
On revealing the gene targets of Ebola virus microRNAs involved in the human skin microbiome [PDF]
PeerJ, 2018 Ebola virus, a negative-sense single-stranded RNA virus, causes severe viral hemorrhagic fever and has a high mortality rate. Histopathological and immunopathological analyses of Ebola virus have revealed that histopathological changes in skin tissue are
Pei-Chun Hsu +2 more
doaj +2 more sources
Frontiers in Public Health, 2023 Ebola is a highly pathogenic virus, which in humans reaches a mortality rate above 50%. Due to a lack of laboratories in territories where Ebola viruses are endemic and the limited number of surveillance programmes, tests for the confirmation of suspected cases of Ebola are often performed in Reference Laboratories.
Bettini, Aurora +2 more
openaire +3 more sources
Postmortem Stability of Ebola Virus
Emerging Infectious Diseases, 2015 The ongoing Ebola virus outbreak in West Africa has highlighted questions regarding stability of the virus and detection of RNA from corpses. We used Ebola virus–infected macaques to model humans who died of Ebola virus disease. Viable virus was isolated
Joseph B. Prescott +5 more
doaj +1 more source
Analysis for fractional dynamics of Ebola virus model
Chaos, Solitons & Fractals, 2020 Heighlights • An iterative scheme is proposed for fractional dynamic of Ebola virus model.• Stability is also discussed.• Entire trajectory of solution is shown.• CPU time taken in iterative scheme is listed.
H. Singh
semanticscholar +1 more source
Plant phenology supports the multi-emergence hypothesis for ebola spillover events [PDF]
, 2017 Ebola virus disease outbreaks in animals (including humans and great apes) start with sporadic host switches from unknown reservoir species. The factors leading to such spillover events are little explored.
Douglas, Noah E. +6 more
core +1 more source