Results 41 to 50 of about 50,978 (164)

Transmission of Ebola Virus Disease: An Overview

Annals of Global Health, 2015
(Uploaded by Plazi for the Bat Literature Project) Ebola is a viral illness of which the initial symptoms can include a sudden fever, intense weakness, muscle pain and a sore throat, according to the World Health Organization (WHO). Airborne transmission of Ebola virus has been hypothesized but not demonstrated in humans.
Suresh Rewar, Dashrath Mirdha
openaire   +3 more sources

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Acceptability and Willingness-to-Pay for a Hypothetical Ebola Virus Vaccine in Nigeria. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:Ebola virus disease is a highly virulent and transmissible disease. The largest recorded fatality from Ebola virus disease epidemic is ongoing in a few countries in West Africa, and this poses a health risk to the entire population of the ...
Maduka Donatus Ughasoro, Dorothy Omono Esangbedo, Beckie Nnenna Tagbo, Ijeoma Chigozie Mejeha   +3 more
doaj   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus

Viruses, 2018
Ebola virus is the causative agent of Ebola virus disease in humans. The lethality of Ebola virus infection is about 50%, supporting the urgent need to develop anti-Ebola drugs.
Qinghua Cui, Han Cheng, Rui Xiong, Gang Zhang, Ruikun Du, Manu Anantpadma, Robert A. Davey, Lijun Rong   +7 more
doaj   +1 more source

Urban wild meat and pangolin consumption across southern forested Cameroon: The limited influence of COVID‐19

People and Nature, EarlyView.
Abstract Overexploitation of wildlife is pervasive in many tropical regions, and in addition to being a significant conservation and sustainability concern, it has received global attention given discussions over the origins of zoonotic disease outbreaks.
Franklin T. Simo, Ghislain F. Difouo, Christian N. Tchana, Alain Christel Wandji, Alfiery Laurel Djomnang‐Nkwala, Marcelle Mbadjoun Nziké, Sévilor Kekeunou, Markéta Swiacká, Daniel J. Ingram   +8 more
wiley   +1 more source

Exposure to Ebola Virus and Risk for Infection with Malaria Parasites, Rural Gabon

Emerging Infectious Diseases, 2020
An association between malaria and risk for death among patients with Ebola virus disease has suggested within-host interactions between Plasmodium falciparum parasites and Ebola virus.
Jessica L. Abbate, Pierre Becquart, Eric Leroy, Vanessa O. Ezenwa, Benjamin Roche   +4 more
doaj   +1 more source

The impact of COVID‐19 on public perceptions of wild meat in Central Africa

People and Nature, EarlyView.
Abstract Wild meat is a significant source of food and income generation in Central Africa. However, there is little knowledge of how the assumed link between COVID‐19 and wild meat consumption has been discussed by the media and received by the public. In this study, we conducted media content analysis of 264 articles published in 2019–2020 related to
Yuhan Li, Lude Kinzonzi, Paul Loundou, Divin Malekani, Krossy Mavakala, Christian Mikolo Yobo, Katharine Abernethy, Matilda Eve Dunn, Donald Midoko Iponga, Robert Mwinyihali, Joss Wright, Eleanor Jane Milner‐Gulland, Lauren Coad, Juliet H. Wright, Daniel W. S. Challender   +14 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

EFFECT OF AWARENESS OF EBOLA VIRUS DISEASE ON FOOD SECURITY STATUS AMONG BUSH MEAT MARKETERS IN IBADAN, OYO STATE, NIGERIA [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2016
The study investigated the effect of level of awareness of Ebola virus disease on food security status among bush meat marketers in Ibadan, Oyo state, Nigeria.
Sikiru Adekunle OLAYIWOLA, Ayobami Idris OLAKUNLE, Amurtiya MICHAEL   +2 more
doaj