Results 41 to 50 of about 93,175 (205)

Postmortem Stability of Ebola Virus

Emerging Infectious Diseases, 2015
The ongoing Ebola virus outbreak in West Africa has highlighted questions regarding stability of the virus and detection of RNA from corpses. We used Ebola virus–infected macaques to model humans who died of Ebola virus disease. Viable virus was isolated
Joseph B. Prescott, Trenton Bushmaker, Robert J. Fischer, Kerri Miazgowicz, Seth D. Judson, Vincent J. Munster   +5 more
doaj   +1 more source

Ebola virus disease epidemic in West Africa: Lessons learned and issues arising from West African countries [PDF]

, 2015
© Royal College of Physicians 2015. All rights reserved.The current Ebola virus disease (EVD) outbreak ravaging three nations in West Africa has affected more than 14,000 persons and killed over 5,000.
Akpalu, AK, Foster, M, Ka, MM, McConnochie, M, Oleribe, OO, Salako, BL, Taylor-Robinson, SD   +6 more
core   +1 more source

Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus

Scientific Reports, 2021
Efficacious therapeutics for Ebola virus disease are in great demand. Ebola virus infections mediated by mucosal exposure, and aerosolization in particular, present a novel challenge due to nontypical massive early infection of respiratory lymphoid ...
Travis K. Warren, Christopher D. Kane, Jay Wells, Kelly S. Stuthman, Sean A. Van Tongeren, Nicole L. Garza, Ginger Donnelly, Jesse Steffens, Laura Gomba, Jessica M. Weidner, Sarah Norris, Xiankun Zeng, Roy Bannister, Tomas Cihlar, Sina Bavari, Danielle P. Porter, Patrick L. Iversen   +16 more
doaj   +1 more source

A review of epidemiological parameters from Ebola outbreaks to inform early public health decision-making. [PDF]

, 2015
The unprecedented scale of the Ebola outbreak in West Africa has, as of 29 April 2015, resulted in more than 10,884 deaths among 26,277 cases. Prior to the ongoing outbreak, Ebola virus disease (EVD) caused relatively small outbreaks (maximum outbreak ...
Bento, AI, Donnelly, CA, Ferguson, NM, Mills, HL, Van Kerkhove, MD   +4 more
core   +1 more source

A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova, V. N. Lebedev, N. V. Karulina, O. V. Chukhralya, S. I. Syromyatnikova, S. V. Borisevich   +5 more
doaj   +1 more source

Ebola Virus Disease, Diagnostics and Therapeutics: Where is the Consensus in Over Three Decades of Clinical Research?

Scientific African, 2021
Ebola virus is a neglected tropical disease widely accepted as one of the most fatal diseases of human and nonhuman primates ever encountered in recent years. For a long time, development of vaccines and anti-Ebola drugs has been slow.
Collins Kipkorir Kebenei, Patrick Okoth
doaj   +1 more source

Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008 [PDF]

, 2012
A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
A Grolla, A MacNeil, A Tuffs, AJ Georges, AM Casillas, B Jeffs, B Le Guenno, Benjamin Jeffs, BS Hewlett, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DH Smith, DL Heymann, E Mupere, ED Johnson, EM Leroy, EM Leroy, Esther Sterk, GA Martini, GA Martini, JL Conrad, Joseph Wamala, JS Gear, JS Towner, Julius Lutwama, K Kibadi, K Mupapa, K Mupapa, KJ Davis, M Borchert, M Bray, M Bray, MA Bwaka, Malcolm Gracie Semple, Maria D. Van Kerkhove, Matthias Borchert, ME Miranda, Michel Van Herp, MJ Bonnet, Natasha Howard, NK Jaax, P Formenty, P Formenty, P Francesconi, P Roddy, P Roddy, Paul Roddy, PE Rollin, Pedro Pablo Palma, PH Sureau, R Colebunders, R Ndambi, R Siegert, RC Baron, Robert Colebunders, RT Emond, S Becker, SF Dowell, SP Fisher-Hoch, SR Zaki, TH Roels, U Stroher, Y Kalongi, Zabulon Yoti   +66 more
core   +3 more sources

Ebola Virus Disease (The Killer Virus): Another Threat to Humans and Bioterrorism: Brief Review and Recent Updates [PDF]

Journal of Clinical and Diagnostic Research, 2015
Ebola virus disease (EVD) described as “one of the world’s most virulent diseases” by WHO was popularly known as Ebola haemorrhagic fever in the past. It is usually considered a severe and deadly illness when humans are concerned.
Deepak Passi, Sarang Sharma, Shubha Ranjan Dutta, Pooja Dudeja, Vivek Sharma   +4 more
doaj   +1 more source

Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity [PDF]

, 2014
Background Ebolaviruses cause a severe and often fatal haemorrhagic fever in humans, with some species such as Ebola virus having case fatality rates approaching 90%. Currently, the worst Ebola virus outbreak since the disease was discovered is occurring
A Groseth, A Pichlmair, A Sanchez, A Topfer, AA Chepurnov, B Hudjetz, BM Connolly, C Trapnell, Christiane Hertz-Fowler, Cyril Empig, D Falzarano, David A Matthews, E Adu-Gyamfi, E Ryabchikova, E Subbotina, EM Leroy, ET Bowen, F Feldmann, G Gabriel, G Liu, GA Marsh, GS Mohan, H Ebihara, HM Weingartl, I Garcia-Dorival, Irene Taylor, Isabel García-Dorival, John Kenny, John N Barr, JR Kugelman, Julian A Hiscox, Kara Corbin-Lickfett, KM Johnson, Kyle Schlunegger, LJ Reed, LR Baden, M Linster, M Martin, M Mateo, M Mehedi, M Mehedi, MA Larkin, Miles W Carroll, N Biedenkopf, N van Doremalen, NA Twenhafel, Neil Hall, O Martinez, Roger Hewson, S Baize, S Herfst, S Pattyn, SA Carroll, SP Reid, Stuart D Dowall, T Hoenen, VA Volchkova, VE Volchkov, VE Volchkov, W Xu, WHO   +60 more
core   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source