Results 51 to 60 of about 93,175 (205)

Ebola Virus RNA in Semen from an HIV-Positive Survivor of Ebola

Emerging Infectious Diseases, 2017
Ebola virus is known to persist in semen of male survivors of Ebola virus disease (EVD). However, maximum duration of, or risk factors for, virus persistence are unknown.
Lawrence J. Purpura, Emerson Rogers, April Baller, Stephen White, Moses Soka, Mary J. Choi, Nuha Mahmoud, Christine Wasunna, Moses Massaquoi, Jomah Kollie, Straker Dweh, Philip Bemah, Victor Ladele, Jonathan Kpaka, Mary Jawara, Margaret Mugisha, Onyekachi Subah, Mylene Faikai, Jeff A. Bailey, Pierre E. Rollin, Barbara J. Marston, Tolbert G. Nyenswah, Alex Gasasira, Barbara Knust, Stuart T. Nichol, Desmond Williams   +25 more
doaj   +1 more source

Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus

Антибиотики и Химиотерапия, 2020
The article presents an analysis of research evaluating the effectiveness of nonspecific means of emergency prevention and treatment of Ebola virus disease.
T. E. Sizikova, v. N. Lebedev, A. A. Petrov, S. V. Borisevich   +3 more
doaj   +1 more source

Awareness of Ebola Virus Disease among the Medical and Non-medical Personnel in Lahore

RADS Journal of Biological Research & Applied Science, 2022
Background: Ebola hemorrhagic fever, also called Ebola Virus Disease (EVD), is caused by a member of Filoviridae family known as Ebola Virus (EBOV).
Waqas Iftikhar, Farah Javed, Maria Nazir, Mussarat Rafiq, Nimra Afzal, Muhammad Babar Khawar   +5 more
doaj   +1 more source

Modernising epidemic science: enabling patient-centred research during epidemics [PDF]

, 2016
Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core   +3 more sources

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

The Ebola virus disease outbreak in Tonkolili district, Sierra Leone: a retrospective analysis of the Viral Haemorrhagic Fever surveillance system, July 2014–June 2015 [PDF]

, 2019
In Sierra Leone, the Ebola virus disease (EVD) outbreak occurred with substantial differences between districts with someone even not affected. To monitor the epidemic, a community event-based surveillance system was set up, collecting data into the ...
Colizzi, Vittorio, DJEUNANG DONGHO, GHYSLAINE BRUNA, Miglietta, Alessandro, Montesano, Carla, Rezza, Giovanni, Russo, Gianluca, Solimini, ANGELO GIUSEPPE, Vullo, Vincenzo   +7 more
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Exposure to Ebola Virus and Risk for Infection with Malaria Parasites, Rural Gabon

Emerging Infectious Diseases, 2020
An association between malaria and risk for death among patients with Ebola virus disease has suggested within-host interactions between Plasmodium falciparum parasites and Ebola virus.
Jessica L. Abbate, Pierre Becquart, Eric Leroy, Vanessa O. Ezenwa, Benjamin Roche   +4 more
doaj   +1 more source

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus

Viruses, 2018
Ebola virus is the causative agent of Ebola virus disease in humans. The lethality of Ebola virus infection is about 50%, supporting the urgent need to develop anti-Ebola drugs.
Qinghua Cui, Han Cheng, Rui Xiong, Gang Zhang, Ruikun Du, Manu Anantpadma, Robert A. Davey, Lijun Rong   +7 more
doaj   +1 more source